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Exocrine pancreatic insufficiency
MONDO:0001684Inability of the exocrine pancreas to produce and secrete an adequate amount of digestive enzymes into the small intestine. Patients present with symptoms of malabsorption syndrome, abdominal discomfort, and bloating. Causes include chronic pancreatitis, cystic fibrosis, and autoimmune disorders.
Also known as: exocrine pancreatic insufficiency, exocrine pancreas insufficiency, pancreatic insufficiency
43 clinical trials for this condition and its sub-types.
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Broader categories
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New device aims to solve feeding problems in ICU patients with organ failure
Symptom relief OngoingThis study tests whether a device called RELiZORB™ can help critically ill adults with multiple organ failure better tolerate tube feedings. The device breaks down fats in the feeding to make them easier to digest. Researchers will compare how well patients meet their nutrition g…
Phase: NA • Sponsor: Inova Health Care Services • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Blood test could spot pancreatic cancer before It's visible
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects blood samples from people with pancreatic diseases to look for markers that might signal pancreatic cancer. The goal is to see if a blood test could detect the cancer earlier than current methods or help track how the disease changes during treatment. Samples …
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New MRI study aims to spot pancreas trouble early
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether MRI scans can help predict pancreas health and complications like diabetes in children and young adults aged 5 to 21. Researchers will compare MRI images with standard tests like endoscopic pancreas function tests and blood work. The goal is to see i…
Phase: PHASE4 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Pancreas transplant weight gain mystery: is extra digestive juice to blame?
Knowledge-focused TerminatedThis study aims to find out if extra digestive juices from the new pancreas cause weight gain after a pancreas transplant. Researchers will measure a digestive enzyme in the stool of 50 transplant recipients and see if it relates to how much weight they gain. The goal is to bette…
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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120,000-Person study hopes to crack the code of chronic illness
Knowledge-focused TerminatedThis observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common dise…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Brain scans reveal hidden links between body diseases and metabolism
Knowledge-focused OngoingThis study watches 200 people with lung, gut, or hormone diseases over time using special brain scans (PET). It aims to see how these diseases change brain activity and whether those changes can predict tumor return, spread, or survival. No new treatment is tested—just observatio…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC