Exercise-induced hyperinsulinism

MONDO:0012396

Exercise-induced hyperinsulinism (EIHI) is a form of diazoxide-sensitive diffuse hyperinsulinism (DHI) characterized by episodes of hypoglycemia induced by exercise due to an inappropriate lactate and pyruvate sensitivity in pancreatic beta-cells.

Also known as: EIHI, MCT1 hyperinsulinism, exercise-induced hyperinsulinemic hypoglycemia, hyperinsulinemic hypoglycemia, familial, type 7, hyperinsulinism due to SLC16A1 deficiency, hyperinsulinism due to monocarboxylate transporter 1 deficiency, monocarboxylate transporter 1 hyperinsulinism, HHF7

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (680) Metabolic disease (233) Hereditary disease (176) Digestive system disorder (160) Endocrine system disorder (72) Glucose metabolism disease (60) Inborn errors of metabolism (45) Pancreas disorder (38) Hyperinsulinism (31) Human disease (14)

Trials to join now! 1

Could a tiny glucagon shot before workout stop blood sugar crashes in type 1 diabetes?

Disease control Recruiting now

This study tests whether a low dose of glucagon, given before exercise, can prevent blood sugar drops in adults with type 1 diabetes who use an automated insulin pump. Eighteen participants will exercise after a meal, comparing glucagon to a standard glucose drink. The goal is to…

Phase: PHASE4 • Sponsor: Steno Diabetes Center Copenhagen • Aim: Disease control

Last updated Aug 15, 2026 00:00 UTC

Exercise-induced hyperinsulinism

Broader categories

Could a tiny glucagon shot before workout stop blood sugar crashes in type 1 diabetes?