Could a tiny glucagon shot before workout stop blood sugar crashes in type 1 diabetes?

NCT ID NCT07427251

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a low dose of glucagon, given before exercise, can prevent blood sugar drops in adults with type 1 diabetes who use an automated insulin pump. Eighteen participants will exercise after a meal, comparing glucagon to a standard glucose drink. The goal is to see if glucagon keeps blood sugar more stable during and after activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-dose glucagon

What this could lead to

If it works, this could offer a new way to prevent exercise-induced low blood sugar in people with type 1 diabetes, reducing reliance on extra carbs.

What could go wrong

This is a small, early-phase trial with only 18 participants, so results may not apply widely. Glucagon can cause nausea or allergic reactions in some people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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  • Contact

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