Epithelial-stromal TGFBI dystrophy
MONDO:0000764Any corneal dystrophy (disease) in which the cause of the disease is a mutation in the TGFBI gene.
Also known as: TGFBI corneal dystrophy (disease), corneal dystrophy (disease) caused by mutation in TGFBI
10 clinical trials for this condition and its sub-types.
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Broader categories
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Can a single Gene-Editing injection stop a blinding corneal disease?
⭐️ CURE ⭐️ Not yet recruitingThis trial tests a single injection of GEB-101, a gene-editing treatment, directly into the cornea of people with TGFBI-related corneal dystrophy, a hereditary condition that causes progressive vision loss. The study aims to see if the treatment is safe and whether it can slow or…
Phase: PHASE1, PHASE2 • Sponsor: GenEditBio Limited • Aim: ⭐️ CURE ⭐️
Last updated Aug 08, 2026 00:03 UTC
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Laser vs. scraping: which eye treatment wins for corneal dystrophy?
Disease control Not yet recruitingThis trial compares two surgical techniques for treating corneal basement membrane dystrophy, a condition that causes blurred vision and painful eye erosions. One method is manual scraping of the damaged corneal layer; the other uses a laser to remove it. The study aims to find w…
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New eye test spots brain fog after cornea surgery
Diagnosis Not yet recruitingThis study checks if a special thinking test (MoCA Blind) can find memory or thinking problems after cornea surgery. It includes 200 adults with cornea disease who will take the test before and 90 days after surgery. The goal is to give doctors a better way to spot these issues i…
Sponsor: The S.N. Fyodorov Eye Microsurgery State Institution • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC