Engraftment syndrome
MONDO:0043358A toxicity of hematopoietic stem cell transplantation that manifests as fever, rash and pulmonary deterioration which becomes evident at marrow engraftment. It occurs unexpectedly and is occasionally fatal. It can occur after an autogeneic or an allogeneic hematopoietic cell transplantation.
Also known as: engraftment syndrome
6 clinical trials for this condition and its sub-types.
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Can a common asthma drug stop post-transplant fevers?
Disease control Recruiting nowThis study tests whether the drug budesonide can prevent fevers caused by engraftment syndrome after a stem cell transplant. About 110 adults with blood cancers will receive budesonide starting 5 days after transplant, and researchers will compare their fever rates to those who d…
Phase: PHASE3 • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New cell prep method aims to tame transplant complications in kids
Disease control AVAILABLEThis study offers a special way to prepare donor stem cells for children and teens under 22 who need a transplant but lack a perfectly matched sibling donor. The method uses the CliniMACS® system to remove certain immune cells, which may help reduce the risk of graft-versus-host …
Sponsor: Victor Aquino • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Can a smartphone app boost sexual health after a stem cell transplant?
Symptom relief Recruiting nowThis study is testing a new digital application called SHIFT to see if it can improve sexual health, quality of life, and reduce distress in people who have had a stem cell or bone marrow transplant. The trial will enroll 300 adult survivors who are at least three months post-tra…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Nerve check may predict transplant complication risk
Knowledge-focused Recruiting nowThis study looks at 60 people getting a stem cell transplant to see if their autonomic nervous system (which controls things like heart rate and sweating) can help predict a serious complication called graft-versus-host disease (GvHD). Participants will have simple nerve tests be…
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC