Encephalomalacia
MONDO:0006741Localized atrophy of the brain parenchyma due to aging, hemorrhage, infarct, or inflammation.
12 clinical trials for this condition and its sub-types.
Follow this condition to get notified about new trialsSub-types
Broader categories
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Cord blood hope: new infusion option for kids with brain damage
Disease control Expanded accessThis program gives children with brain disorders like cerebral palsy or stroke access to umbilical cord blood infusions. The treatment uses donated cord blood cells to help repair brain damage. Kids up to age 26 with normal immune function may qualify. The goal is to improve symp…
Sponsor: Joanne Kurtzberg, MD • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Common allergy drug may heal brain damage in preterm infants
Disease control Recruiting nowThis study tests whether clemastine, an allergy medicine, is safe for premature babies with white matter injury—a common brain injury in infants born early. Researchers will give the drug by mouth to 24 babies born at or before 32 weeks and now between 35 and 41 weeks old. The go…
Phase 1 • Sponsor: Bridget LaMonica Ostrem, M.D., Ph.D. • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Simple baby exercises may boost brain development in preemies
Disease control Recruiting nowThis study tests whether early physiotherapy, taught to parents, can improve movement and development in babies at risk for problems like cerebral palsy. Fifty infants from the NICU will be randomly assigned to get either the special program or standard care. Researchers will mea…
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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5-Minute MRI could solve brain tumor mystery after radiation
Diagnosis Recruiting nowThis study is testing a new, quick MRI technique called Magnetic Resonance Fingerprinting (MRF) to better tell the difference between a brain tumor coming back and damage from radiation therapy (radiation necrosis). About 90 people will take part, including healthy volunteers, pa…
Sponsor: Case Comprehensive Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Infant brain recovery study seeks clues to heal stroke damage
Knowledge-focused Recruiting nowThis study follows 65 infants who had a stroke around birth, tracking their brain development and motor skills over two years. Researchers use MRI scans, brain stimulation, and movement tests to find markers of recovery. The goal is to understand how the brain heals, which could …
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New study aims to catch hidden vision problems in infants early
Knowledge-focused Recruiting nowThis study follows 60 infants at high risk for Cerebral Visual Impairment (CVI), a brain-based vision problem often missed until later childhood. Researchers will collect data from clinical exams, brain scans, and vision tests up to 24 months of age. The goal is to create a model…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC