Cure My Disease

Don't miss your cure!

Log in / Sign up

Dysplasia of the proximal femoral epiphyses

MONDO:1030002

A developmental disorder affecting the growth and development of the proximal end of the femur (thigh bone) near the hip joint characterized by avascular necrosis of the femoral head, cystic changes of the femoral head, and/or sclerosis of the femoral head. It is a relatively milder form of the other skeletal disorders associated with COL2A1.

37 clinical trials for this condition and its sub-types.

Follow this condition to get notified about new trials

Sub-types

Avascular necrosis of femoral head, primary, 1 (34) Legg-Calve-Perthes disease (9) Mild spondyloepiphyseal dysplasia due to COL2A1 mutation with early-onset osteoarthritis (0)

Broader categories

Disease (717) Musculoskeletal system disorder (214) Hereditary disease (188) Connective tissue disorder (68) Bone disorder (51) Syndromic disease (25) Human disease (15) Skeletal system disorder (4) Collagenopathy (3) Disease of genetic or genomic mechanism (2)

Trials to join now! 13 Not yet recruiting 1 Not yet finished but already full! 17 Completed 4 Terminated 2

Oxygen therapy may boost hip procedure for bone death

Disease control Not yet recruiting

This study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to a standard hip procedure (core decompression with bone marrow cells) can reduce pain in people with early-stage avascular necrosis of the hip. The trial will enroll 400 p…

Sponsor: Yale University • Aim: Disease control

Last updated Jul 03, 2026 00:00 UTC