Dentinogenesis imperfecta
MONDO:0018849Dentinogenesis imperfecta (DGI) is a hereditary dentin defect characterized by abnormal dentin structure resulting in abnormal tooth development.
Also known as: DGI, DGI without OI, DI, dentinogenesis imperfecta, dentinogenesis imperfecta (disease), dentinogenesis imperfecta without osteogenesis imperfecta, non-syndromic DGI, non-syndromic dentinogenesis imperfecta
3 clinical trials for this condition and its sub-types.
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Broader categories
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3D-Printed teeth: a better fit for kids?
Disease control CompletedThis trial tests whether 3D-printed crowns work better than standard stainless-steel crowns for restoring damaged first permanent molars in children. The study will compare how well each crown holds up, its effect on gum health, and how satisfied children and parents are with the…
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Hunting for hidden genes behind tooth defects
Knowledge-focused CompletedThis study aims to discover new genes and mutations that cause isolated forms of amelogenesis imperfecta and dentinogenesis imperfecta—inherited conditions that affect tooth enamel and dentin. Researchers are using whole exome sequencing on participants who have these tooth disor…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC