Cyclic vomiting syndrome
MONDO:0010778A rare functional disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting separated by symptom-free intervals. Episodes are often accompanied by pallor, lethargy, and abdominal pain. The condition shows a strong association with migraine headaches and may have maternal inheritance patterns suggestive of mitochondrial involvement.
Also known as: cyclic vomiting syndrome, CVS, Cvs-plus, cyclic vomiting syndrome with neuromuscular disease, cyclic vomiting syndrome-plus
8 clinical trials for this condition and its sub-types.
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Could a 'Stomach Pacemaker' stop Kids' chronic nausea?
Symptom relief CompletedThis study tested whether a device that sends small electrical pulses to the stomach can help children with severe, long-lasting nausea and vomiting. Thirty kids who hadn't gotten better with standard treatments took part. Each child had a temporary pacing lead placed through a t…
Phase: NA • Sponsor: Nationwide Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Ear zapper may ease debilitating vomiting episodes
Symptom relief CompletedThis pilot study tested a small device that stimulates nerves in the ear to help people with cyclic vomiting syndrome, a condition causing repeated bouts of severe nausea and vomiting. Forty-seven children and adults used the device either during an episode or daily for six weeks…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC