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Cyclic vomiting syndrome
MONDO:0010778A rare functional disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting separated by symptom-free intervals. Episodes are often accompanied by pallor, lethargy, and abdominal pain. The condition shows a strong association with migraine headaches and may have maternal inheritance patterns suggestive of mitochondrial involvement.
Also known as: cyclic vomiting syndrome, CVS, Cvs-plus, cyclic vomiting syndrome with neuromuscular disease, cyclic vomiting syndrome-plus
13 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could a 'Stomach Pacemaker' stop Kids' chronic nausea?
Symptom relief CompletedThis study tested whether a device that sends small electrical pulses to the stomach can help children with severe, long-lasting nausea and vomiting. Thirty kids who hadn't gotten better with standard treatments took part. Each child had a temporary pacing lead placed through a t…
Phase: NA • Sponsor: Nationwide Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Ear zapper may ease debilitating vomiting episodes
Symptom relief CompletedThis pilot study tested a small device that stimulates nerves in the ear to help people with cyclic vomiting syndrome, a condition causing repeated bouts of severe nausea and vomiting. Forty-seven children and adults used the device either during an episode or daily for six weeks…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Researchers measure breathing, strength, and quality of life in hospitalized endocrine patients
Knowledge-focused CompletedThis completed observational study at Uşak University examined 150 adults hospitalized in the endocrinology department. Researchers measured breathing, muscle strength, pain, fatigue, sleep quality, physical activity, balance, and nerve function. The goal was to better understand…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC