Cryopyrin-associated periodic syndrome
MONDO:0016168Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease. CAPS comprises 3 disorders on a continuum of severity: severe CINCA syndrome, intermediate Muckle-Wells syndrome (MWS) and milder familial cold urticaria (FCAS).
Also known as: caps, Cryopyrinopathy
21 clinical trials for this condition and its sub-types, 10 tagged with Cryopyrin-associated periodic syndrome itself.
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Browse by category →Sub-types of Cryopyrin-associated periodic syndrome
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CINCA syndrome 4 trials
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Muckle-Wells syndrome 3 trials
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4 sub-types
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NIH launches major study to unlock secrets of rare inflammatory diseases
Knowledge-focused CompletedThis study follows up to 5,000 people with autoinflammatory diseases (like NOMID, CANDLE, and juvenile dermatomyositis) and their healthy relatives. Researchers will collect medical history, blood samples, and imaging over 2-5 day visits to learn how these diseases work and find …
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Scientists probe genetic roots of Cold-Triggered hives
Knowledge-focused CompletedThis study looks at why some people develop hives from physical triggers like cold, pressure, or sunlight. Researchers will test participants' skin reactions and collect blood and genetic samples to understand the role of immune cells and genes. The goal is to uncover the underly…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New tool aims to capture daily life with rare inflammatory diseases
Knowledge-focused CompletedThis study involved 39 adults and children with autoinflammatory diseases like FMF and Still's disease. Researchers conducted interviews to understand how these conditions affect quality of life. The goal was to create a tool that doctors can use to better assess and address pati…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC