Congenital laryngeal palsy
MONDO:0015316Congenital laryngeal palsy is a rare larynx anomaly characterized by unilateral or bilateral paralysis of the vocal cords as a result of dysfunction of the motor nerve supply to the larynx. Patients typically present at birth (or shortly thereafter) with stridor, weak or breathy cry, dysphonia or aphonia, feeding or aspiration difficulties and, occasionally, respiratory compromise. Neurological disease, masses that cause compression and aberrant vessels are often associated. Most cases resolve spontaneously over 6-12 months.
Also known as: congenital vocal cord paralysis
18 clinical trials for this condition and its sub-types.
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Electric pacing device aims to restore breathing and voice in paralyzed larynx patients
Disease control OngoingThis study tests a new device that electrically stimulates the voice box muscles in people with bilateral vocal fold paralysis, a condition where both vocal cords are stuck closed. The main goal is to see if the device is safe and can improve breathing and voice quality. Eight ad…
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New pacemaker for paralyzed vocal cords aims to restore breathing
Disease control OngoingThis study tests a new device called the SPIRION Laryngeal Pacemaker in 20 people with bilateral vocal cord paralysis, a condition that narrows the airway and makes breathing difficult. The device is implanted to help open the vocal cords during breathing. The main goals are to c…
Phase: NA • Sponsor: MED-EL Elektromedizinische Geräte GesmbH • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New study tracks voice recovery after throat surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 500 adults with vocal cord paralysis or atrophy who undergo laryngeal framework surgery. Researchers will track voice quality, swallowing ability, and complication rates for two years after surgery. The goal is to understand which surgical techniques work best …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New breath test could replace painful lung scopes
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to see if a simple, non-invasive breathing test can accurately measure the acidity (pH) in the airways, which is often abnormal in lung diseases. Researchers will compare results from this breath test with standard methods in 150 healthy volunteers and people with…
Phase: PHASE2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC