Congenital laryngeal palsy
MONDO:0015316Congenital laryngeal palsy is a rare larynx anomaly characterized by unilateral or bilateral paralysis of the vocal cords as a result of dysfunction of the motor nerve supply to the larynx. Patients typically present at birth (or shortly thereafter) with stridor, weak or breathy cry, dysphonia or aphonia, feeding or aspiration difficulties and, occasionally, respiratory compromise. Neurological disease, masses that cause compression and aberrant vessels are often associated. Most cases resolve spontaneously over 6-12 months.
Also known as: congenital vocal cord paralysis
18 clinical trials for this condition and its sub-types.
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Nerve surgery gives voice and breath back to paralyzed vocal cords
Disease control CompletedThis study tested a surgery that reconnects nerves in the throat to help people with both vocal cords paralyzed. The goal was to improve breathing and voice without causing swallowing problems. Four adults who had not gotten good results from earlier treatments took part. Results…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Oxygen technique during throat surgery may impact heart function
Knowledge-focused CompletedThis study looked at how using high-flow nasal oxygen during laryngeal surgery affects the heart and blood vessels. Twenty relatively healthy adults were monitored for changes in heart function compared to standard breathing support. The goal was to understand potential risks, no…
Phase: NA • Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New breathing technique may reduce lung injury risk in throat surgery
Knowledge-focused CompletedThis completed study tested two ways of helping patients breathe during microscopic throat surgery. One method uses a steady airflow, while the other uses a set volume of air. The goal was to see which method keeps airway pressure lower and safer. 68 adults having elective laser …
Phase: NA • Sponsor: Kocaeli University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC