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Choroideremia

MONDO:0010557

Choroideremia (CHM) is an X-linked chorioretinal dystrophy characterized by progressive degeneration of the choroid, retinal pigment epithelium (RPE) and retina.

Also known as: CHM, Tapetochoroidal dystrophy, choroideremia, progressive choroidal atrophy, TCD, Tapetochoroidal dystrophy, progressive, choroidal sclerosis, progressive tapetochoroidal dystrophy

31 clinical trials for this condition and its sub-types.

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Sub-types

Choroideremia hypopituitarism (0) Total central choroidal atrophy (0)

Broader categories

Cardiovascular disorder (1051) Disease (680) Nervous system disorder (231) Hereditary disease (176) Vascular disorder (135) Eye disorder (102) Retinal disorder (85) Inherited retinal dystrophy (40) Retinal degeneration (40) Perceptual disorders (22)
Trials to join now! 15 Not yet recruiting 3 Not yet finished but already full! 1 Completed 10 Terminated 2
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  • Gene therapy injection aims to restore sight in rare eye diseases

    Disease control Ongoing

    This early-phase trial tests a single injection of a gene therapy called RTx-015 in 10 adults with retinitis pigmentosa or choroideremia, two inherited conditions that cause vision loss. The therapy delivers a gene that makes retinal cells produce a light-sensitive protein, poten…

    Phase: PHASE1 • Sponsor: Ray Therapeutics, Inc. • Aim: Disease control

    Last updated Jun 27, 2026 09:07 UTC

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