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Childhood neoplasm
MONDO:0021079A benign or malignant neoplasm arising during childhood.
Also known as: childhood neoplasm, childhood neoplasm (disease), childhood tumor, childhood tumour, neoplasm (disease) of childhood, paediatric neoplasm, paediatric neoplasm (disease), paediatric tumour
2050 clinical trials for this condition and its sub-types, 46 tagged with Childhood neoplasm itself.
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Sub-types of Childhood neoplasm
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Childhood malignant neoplasm 239 trials · 598 incl. sub-types
30 sub-types
- Childhood leukemia 23 trials · 172 incl. sub-types Sub-types →
- Pediatric lymphoma 3 trials · 141 incl. sub-types Sub-types →
- Childhood brain stem neoplasm 3 trials · 95 incl. sub-types Sub-types →
- Pediatric hepatocellular carcinoma 36 trials
- Childhood malignant kidney neoplasm 0 trials · 30 incl. sub-types Sub-types →
- Pediatric high-grade glioma 14 trials · 16 incl. sub-types Sub-types →
- Childhood precursor T-lymphoblastic lymphoma/leukemia 0 trials · 13 incl. sub-types Sub-types →
- Pediatric osteosarcoma 8 trials Sub-types →
- Childhood central nervous system primitive neuroectodermal neoplasm 6 trials Sub-types →
- Pleuropulmonary blastoma 4 trials Sub-types →
- Malignant childhood germ cell neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Pediatric fibrosarcoma 0 trials · 2 incl. sub-types Sub-types →
- Pediatric intraocular retinoblastoma 2 trials
- Childhood choroid plexus carcinoma 1 trial
- Childhood malignant schwannoma 1 trial
- Childhood oligodendroglioma 1 trial
- Extrarenal rhabdoid tumor 1 trial
- Childhood botryoid rhabdomyosarcoma 0 trials Sub-types →
- Childhood cerebral astrocytoma 0 trials Sub-types →
- Childhood epithelioid sarcoma 0 trials
- Childhood malignant melanoma 0 trials Sub-types →
- Childhood malignant mesenchymoma 0 trials
- Childhood pleomorphic rhabdomyosarcoma 0 trials
- Pediatric angiosarcoma 0 trials
- Pediatric extraocular retinoblastoma 0 trials
- Pediatric infratentorial ependymoma 0 trials
- Pediatric liposarcoma 0 trials
- Pediatric mesenchymal chondrosarcoma 0 trials
- Pediatric myxoid chondrosarcoma 0 trials
- Pediatric supratentorial ependymoma 0 trials
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Childhood infratentorial neoplasm 1 trial · 109 incl. sub-types
4 sub-types
- Childhood brain stem neoplasm 3 trials · 95 incl. sub-types Sub-types →
- Childhood cerebellar neoplasm 0 trials · 14 incl. sub-types Sub-types →
- Pediatric infratentorial ependymoblastoma 0 trials
- Pediatric infratentorial ependymoma 0 trials
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Childhood kidney neoplasm 1 trial · 30 incl. sub-types
3 sub-types
- Childhood malignant kidney neoplasm 0 trials · 30 incl. sub-types Sub-types →
- Childhood multilocular cystic kidney neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Childhood kidney angiomyolipoma 0 trials
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Childhood ependymoma 7 trials
1 sub-type
- Pediatric supratentorial ependymoma 0 trials
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Childhood germ cell tumor 3 trials · 7 incl. sub-types
4 sub-types
- Malignant childhood germ cell neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Childhood central nervous system germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
- Childhood gonadal germ cell tumor 1 trial · 2 incl. sub-types Sub-types →
- Pediatric ovarian germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
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Childhood astrocytic tumor 1 trial · 2 incl. sub-types
4 sub-types
- Childhood pilocytic astrocytoma 1 trial Sub-types →
- Childhood brainstem astrocytoma 0 trials
- Childhood cerebellar astrocytic neoplasm 0 trials
- Childhood cerebral astrocytoma 0 trials Sub-types →
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Childhood optic nerve glioma 1 trial
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Childhood spinal cord tumor 1 trial
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Childhood choroid plexus neoplasm 0 trials · 1 incl. sub-types
1 sub-type
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Childhood carcinoid tumor 0 trials
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Childhood testicular neoplasm 0 trials
1 sub-type
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Pediatric meningioma 0 trials
2 sub-types
- Childhood brain meningioma 0 trials
- Pediatric leptomeningeal melanoma 0 trials
Most studied deeper sub-types
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New immunotherapy combo tested in kids with Hard-to-Treat cancers
Disease control OngoingThis study is testing two immunotherapy drugs, durvalumab and tremelimumab, in children and teens up to age 17 with advanced solid tumors or blood cancers that have not responded to standard treatments. The first part finds the safest dose, and the second part checks if the drugs…
Phase 1/2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Engineered immune cells take aim at childhood cancers in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a protein called B…
Phase 1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Immune cells injected into brain tumors: a new hope for kids?
Disease control PausedThis early-phase trial tests whether natural killer (NK) cells from healthy donors can be safely injected into the brain tumors of children and young adults whose cancer has returned or is growing. The NK cells are specially treated to resist the tumor's defenses. The main goals …
Phase 1 • Sponsor: Sabine Mueller, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New radioactive drug targets childhood cancers that Won't quit
Disease control OngoingThis early-stage trial tests a radioactive drug called CLR 131 in 30 children and young adults with solid tumors, lymphoma, or brain tumors that have come back or not responded to standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors. P…
Phase 1 • Sponsor: Cellectar Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Engineered immune cells take on childhood cancers in first human test
Disease control OngoingThis early-stage trial tests a new type of immunotherapy for children and young adults with solid tumors that have not responded to standard treatments. The therapy uses the patient's own immune cells (T cells) that are genetically modified to recognize and attack cancer cells ca…
Phase 1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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15-Year study tracks hidden risks of gene therapy in children
Knowledge-focused By invitation onlyThis study follows 500 children and young adults who received gene therapy for cancer as part of earlier trials. Researchers will monitor them for up to 15 years to detect any delayed side effects. Participants have blood tests and health check-ups at regular intervals. No new tr…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Cancer's hidden toll: young kids miss key social milestones
Knowledge-focused OngoingThis study looks at how cancer and its treatment impact social and emotional development in children aged 4 to 6. About 119 children with brain or solid tumors will complete questionnaires and tasks to measure social skills, thinking abilities, and play behavior. The goal is to u…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can tumor profiling help kids beat cancer? new study aims to find out
Knowledge-focused OngoingThis study looks at whether testing the genes of a child's solid tumor can help doctors choose a more effective treatment. About 825 children and young adults with hard-to-treat solid tumors will have their tumors genetically profiled. The goal is to see if those who receive a tr…
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC