Cervical intraepithelial neoplasia grade 2/3
MONDO:0006137A neoplastic process in the cervix characterized by morphologic features of both moderate and severe intraepithelial neoplasia.
Also known as: CIN 2/3
37 clinical trials for this condition and its sub-types.
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Can a portable heat device match cryotherapy for cervical precancer?
Disease control CompletedThis trial tests whether portable thermal ablation devices, designed for low-resource settings, can treat cervical precancer as effectively as standard cryotherapy. Women aged 18 and older with high-grade cervical precancer will receive either cryotherapy or thermal ablation with…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Could a cream after surgery stop cervical cancer in HIV-Positive women?
Disease control CompletedThis study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is an acceptable and feasible way to treat cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it a…
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New study aims to find the best way to catch HPV cancers early in HIV patients
Diagnosis CompletedThis study looks at which tests work best to find early signs of HPV-related cancer in the cervix or anus of people living with HIV. About 1,586 participants from Mexico and Puerto Rico will be tested using different methods, including HPV tests and cell samples. The goal is to c…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Diagnosis
Last updated Aug 13, 2026 00:00 UTC
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New Self-Test could revolutionize cervical cancer screening
Diagnosis CompletedThis study tested a new way to screen for cervical cancer using samples women collect themselves at home. Researchers wanted to see if a test that looks at DNA changes in HPV could better identify who truly needs follow-up care. About 294 women participated, and the goal was to m…
Sponsor: George Washington University • Aim: Diagnosis
Last updated Jun 27, 2026 09:10 UTC
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Smarter screening: could a simple score reduce unnecessary biopsies?
Diagnosis CompletedThis study tested a new colposcopy method that uses a scoring system (Swede score) to better diagnose cervical precancer in women with abnormal screening results. Researchers enrolled 929 women referred for colposcopy to see if the scoring system could accurately identify precanc…
Sponsor: University of Aarhus • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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Can the HPV vaccine stop cervical abnormalities from returning after surgery?
Prevention CompletedThis study looked at whether giving the Gardasil 9 HPV vaccine to women at the same time as surgery for abnormal cervical cells (CIN) can help clear the virus and prevent future infections. About 1,100 women aged 18-55 took part. The goal was to see if the vaccine reduces the cha…
Phase: PHASE3 • Sponsor: Imperial College London • Aim: Prevention
Last updated Jun 27, 2026 12:28 UTC