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Cerebral folate deficiency

MONDO:0100034

Cerebral folate deficiency is defined as a neurological syndrome associated with low CSF 5-methyltetrahydrofolate (5MTHF), the active folate metabolite, in the presence of normal folate metabolism outside the nervous system. Cerebral folate deficiency can result from either disturbed folate transport or from increased folate turnover within the central nervous system.

11 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Metabolic disease (233) Nutritional deficiency disease (221) Hereditary disease (176) Nutritional disorder (129) Inborn errors of metabolism (45) Human disease (14) Vitamin deficiency disorder (9) Disease of genetic or genomic mechanism (2) Disease by developmental or physiological process (0)
Trials to join now! 4 Not yet recruiting 3 Not yet finished but already full! 1 Completed 3
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  • Real food tube feeds: a kinder option for kids?

    Symptom relief Ongoing

    This study looks at how well children aged 1 to 16 tolerate and accept new nutritional feeds made from real food ingredients. The feeds are given through a tube or as a drink. Researchers will track stomach issues like pain, bloating, and nausea over 28 days. The goal is to see i…

    Phase: NA • Sponsor: Nutricia UK Ltd • Aim: Symptom relief

    Last updated Jun 27, 2026 12:08 UTC

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