Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2
MONDO:0014768Any CADASIL in which the cause of the disease is a mutation in the HTRA1 gene.
Also known as: CADASIL caused by mutation in HTRA1, CADASIL type 2, CADASIL2, HTRA1 CADASIL, cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2
144 clinical trials for this condition and its sub-types.
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Broader categories
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC