Central nervous system cancer
MONDO:0002714A malignant neoplasm involving the central nervous system
Also known as: CNS neoplasm, central nervous system tumor, central nervous system tumour, CNS cancer, CNS malignant neoplasms, CNS neoplasms, malignant, cancer of CNS, cancer of central nervous system
4377 clinical trials for this condition and its sub-types, 131 tagged with Central nervous system cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central nervous system cancer
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Malignant glioma 250 trials · 920 incl. sub-types
12 sub-types
- High grade astrocytic tumor 8 trials · 673 incl. sub-types Sub-types →
- Brain glioma 29 trials · 210 incl. sub-types Sub-types →
- Grade III glioma 44 trials · 88 incl. sub-types Sub-types →
- Oligodendroglial tumor 2 trials · 73 incl. sub-types Sub-types →
- Malignant peripheral nerve sheath tumor 36 trials · 38 incl. sub-types Sub-types →
- Pediatric high-grade glioma 14 trials · 16 incl. sub-types Sub-types →
- Spinal cord glioma 3 trials Sub-types →
- Granular cell cancer 1 trial · 2 incl. sub-types Sub-types →
- Malignant perineurioma 1 trial
- Isolated melanotic schwannoma 0 trials
- Neurofibroma of gallbladder 0 trials
- Neurofibroma of the heart 0 trials
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Brain cancer 682 trials · 902 incl. sub-types
9 sub-types
- Metastatic malignant neoplasm in the brain 267 trials
- Brain glioma 29 trials · 210 incl. sub-types Sub-types →
- Infratentorial cancer 4 trials · 105 incl. sub-types Sub-types →
- Supratentorial cancer 15 trials · 49 incl. sub-types Sub-types →
- Cerebral ventricle cancer 0 trials · 13 incl. sub-types Sub-types →
- Intracranial primitive neuroectodermal tumor 0 trials · 8 incl. sub-types Sub-types →
- Brain germinoma 1 trial · 4 incl. sub-types Sub-types →
- Cancer of cerebellum 1 trial
- Brain sarcoma 0 trials Sub-types →
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Primary central nervous system lymphoma 92 trials · 103 incl. sub-types
3 sub-types
- Central nervous system non-hodgkin lymphoma 1 trial · 22 incl. sub-types Sub-types →
- Cerebral lymphoma 2 trials
- Spinal cord lymphoma 0 trials
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Central nervous system sarcoma 2 trials · 74 incl. sub-types
12 sub-types
- Malignant peripheral nerve sheath tumor 36 trials · 38 incl. sub-types Sub-types →
- Atypical teratoid rhabdoid tumor 35 trials · 36 incl. sub-types Sub-types →
- Brain sarcoma 0 trials Sub-types →
- Central nervous system angiosarcoma 0 trials
- Central nervous system extraskeletal osteosarcoma 0 trials
- Central nervous system fibrosarcoma 0 trials
- Central nervous system leiomyosarcoma 0 trials Sub-types →
- Central nervous system rhabdomyosarcoma 0 trials
- Intracranial extraskeletal myxoid chondrosarcoma 0 trials
- Isolated melanotic schwannoma 0 trials
- Meningeal sarcoma 0 trials Sub-types →
- Spinal cord sarcoma 0 trials
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Spinal cord cancer 21 trials · 57 incl. sub-types
8 sub-types
- Metastatic malignant neoplasm in the spinal cord 38 trials
- Spinal cord glioma 3 trials Sub-types →
- Spinal cord lymphoma 0 trials
- Spinal cord melanoma 0 trials
- Spinal cord neuroblastoma 0 trials
- Spinal cord primitive neuroectodermal tumor 0 trials
- Spinal cord sarcoma 0 trials
- Spinal meninges cancer 0 trials
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Central nervous system primitive neuroectodermal neoplasm 8 trials · 24 incl. sub-types
8 sub-types
- Intracranial primitive neuroectodermal tumor 0 trials · 8 incl. sub-types Sub-types →
- Childhood central nervous system primitive neuroectodermal neoplasm 6 trials Sub-types →
- Ependymoblastoma 5 trials Sub-types →
- Ganglioneuroma 5 trials Sub-types →
- Central nervous system tumor with bcor internal tandem duplication 1 trial
- Adult central nervous system primitive neuroectodermal neoplasm 0 trials Sub-types →
- Spinal cord neuroblastoma 0 trials
- Spinal cord primitive neuroectodermal tumor 0 trials
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Central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor 1 trial · 22 incl. sub-types
4 sub-types
- Esthesioneuroblastoma 9 trials
- Embryonal tumor with multilayered rosettes 8 trials
- Ependymoblastoma 5 trials Sub-types →
- Medulloepithelioma 3 trials
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Malignant tumor of meninges 0 trials · 14 incl. sub-types
10 sub-types
- Anaplastic meningioma 9 trials
- Malignant leptomeningeal tumor 3 trials · 4 incl. sub-types Sub-types →
- Cerebral meningioma 0 trials · 1 incl. sub-types Sub-types →
- Intraventricular meningioma 0 trials Sub-types →
- Lung meningioma 0 trials
- Meningeal melanomatosis 0 trials
- Meningeal sarcoma 0 trials Sub-types →
- Meninges hemangiopericytoma 0 trials
- Skin meningioma 0 trials Sub-types →
- Spinal meninges cancer 0 trials
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Malignant adrenal gland pheochromocytoma 11 trials
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Central nervous system germinoma 2 trials · 4 incl. sub-types
3 sub-types
- Brain germinoma 1 trial · 4 incl. sub-types Sub-types →
- Childhood central nervous system germinoma 1 trial Sub-types →
- Adult central nervous system germinoma 0 trials
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Central nervous system melanocytic neoplasm 1 trial · 4 incl. sub-types
3 sub-types
- Primary melanoma of the central nervous system 2 trials · 3 incl. sub-types Sub-types →
- Meningeal melanocytoma 1 trial
- Diffuse meningeal melanocytosis 0 trials
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Central nervous system endodermal sinus tumor 0 trials · 1 incl. sub-types
1 sub-type
- Pineal region yolk sac tumor 1 trial
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3 sub-types
- Adult central nervous system choriocarcinoma 0 trials
- Pediatric CNS choriocarcinoma 0 trials
- Pineal region choriocarcinoma 0 trials
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2 sub-types
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Malignant carotid body paraganglioma 0 trials
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3 sub-types
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2 sub-types
Most studied deeper sub-types
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Tumor profiling may unlock targeted drug options for pediatric cancers
Diagnosis Not yet recruitingThis study tests whether a two-step tumor profiling approach can reliably measure antibody-drug conjugate (ADC) target proteins in children and young adults with relapsed or refractory solid or central nervous system tumors. The approach uses bulk RNA sequencing to screen for tar…
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Sep 02, 2026 00:00 UTC
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Video chat with nurse may ease brain cancer anxiety before treatment
Symptom relief Not yet recruitingThis study tests whether a teleconsultation with a specially trained nurse can reduce psychological distress in adults recently diagnosed with a primary brain tumor. 58 participants will be randomly assigned to receive either usual care or usual care plus one nurse-led video call…
Sponsor: Centre Hospitalier Universitaire de la Réunion • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Can a Child's own words improve cancer care?
Knowledge-focused Not yet recruitingThis study asks whether a simple questionnaire, called SSPedi, can capture the symptoms that children with brain or spinal cord tumors experience while on new cancer therapies. Children aged 2 to 18 who are already part of a larger French study (SACHA) will use an app to report t…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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New program aims to make cancer surgery safer for seniors
Knowledge-focused Not yet recruitingThis study looks at how a special program, called the Geriatric Surgery Verification Program, works at the James Cancer Hospital. The program helps doctors and nurses better care for patients aged 65 and older who need cancer surgery. It includes checking for age-related issues l…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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AI reads brain tumor types from routine slides, no special stains needed
Knowledge-focused Not yet recruitingThis study develops an artificial intelligence model that can classify brain tumors into categories, families, and specific diagnoses using only standard stained tissue slides. Researchers will train the AI on 20,000 archived images from two hospitals and test its accuracy agains…
Sponsor: Huashan Hospital • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC