Central diabetes insipidus
MONDO:0015790Central diabetes insipidus (CDI) is a hypothalamus-pituitary disease characterized by polyuria and polydipsia due to a vasopressin (AVP) deficiency. It can be inherited or acquired (hereditary CDI and acquired CDI).
Also known as: CDI, neurogenic diabetes insipidus, diabetes insipidus cranial type, diabetes insipidus neurogenic, diabetes insipidus neurohypophyseal
12 clinical trials for this condition and its sub-types, 5 tagged with Central diabetes insipidus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central diabetes insipidus
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Neurohypophyseal diabetes insipidus 9 trials
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Acquired central diabetes insipidus 0 trials
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Could a cocktail of good bacteria break the cycle of c. diff?
Disease control Recruiting nowThis large Phase 3 trial tests whether VE303, a capsule containing 8 harmless bacteria, can prevent repeat Clostridioides difficile (C. diff) infections. About 852 people who have had at least one prior C. diff infection will take VE303 or a placebo for 14 days. The main goal is …
Phase 3 • Sponsor: Vedanta Biosciences, Inc. • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can the 'love hormone' calm anxiety in diabetes insipidus?
Symptom relief Recruiting nowThis study tests whether a nasal spray containing oxytocin can help reduce anxiety and improve emotional well-being in adults with central diabetes insipidus, a condition where the body lacks a key hormone. Participants will receive either oxytocin or a placebo spray for several …
Phase 2 • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can a 'Love Hormone' spray boost sexual health in diabetes insipidus?
Symptom relief Recruiting nowThis phase 2 trial tests whether oxytocin nasal spray can improve sexual well-being in people with central diabetes insipidus, a condition that also causes oxytocin deficiency. The study includes 42 participants (patients and healthy controls) and uses a double-blind, placebo-con…
Phase 2 • Sponsor: University Hospital, Basel, Switzerland • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Blood marker may predict brain surgery complication in kids
Knowledge-focused Recruiting nowThis study looks at whether measuring a substance called copeptin in the blood can help doctors diagnose central diabetes insipidus (CDI) in children after brain surgery. CDI causes extreme thirst and frequent urination due to a hormone imbalance. The study will track copeptin le…
Sponsor: Children's Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC