Catecholaminergic polymorphic ventricular tachycardia
MONDO:0017990Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe genetic arrhythmogenic disorder characterized by adrenergically induced ventricular tachycardia (VT) manifesting as syncope and sudden death.
Also known as: CPVT, bidirectional tachycardia induced by catecholamine, catecholaminergic polymorphic ventricular tachycardia, double tachycardia induced by catecholamines, malignant paroxysmal ventricular tachycardia, multifocal ventricular premature beats, ventricular tachycardia, catecholaminergic polymorphic, catecholamine-induced polymorphic ventricular tachycardia
42 clinical trials for this condition and its sub-types, 9 tagged with Catecholaminergic polymorphic ventricular tachycardia itself.
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Sub-types of Catecholaminergic polymorphic ventricular tachycardia
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Long QT syndrome 16 0 trials
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Gene therapy trial aims to tame deadly heart rhythms
Disease control Recruiting nowThis early-stage trial tests a single dose of SGT-501, a gene therapy given by IV, in 18 people with a rare inherited heart condition called CPVT that can cause dangerous fast heartbeats during exercise or stress. The main goal is to check safety and find the right dose in adults…
Phase 1 • Sponsor: Solid Biosciences Inc. • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New drug aims to tame rare, Exercise-Triggered heart condition
Disease control Recruiting nowThis study tests an experimental drug called CRD-4730 in 12 adults with a rare inherited heart condition (CPVT) that can cause dangerous heart rhythms during exercise or stress. Participants will receive two different doses of the drug and a placebo in random order to see if it s…
Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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New pill could tame deadly heart flutters during exercise
Disease control Recruiting nowThis study tests a new oral drug called AGP100 in people with a rare inherited heart condition (CPVT) that can cause dangerously fast heartbeats during stress or exercise. Ten adults aged 18-75 will take three different doses of AGP100 over six weeks while continuing their usual …
Phase 2 • Sponsor: Agiana Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New heart test could predict sudden cardiac death risk
Diagnosis Recruiting nowThis study aims to develop a new clinical test to diagnose Calcium Release Deficiency Syndrome (CRDS), a rare inherited heart condition that increases the risk of sudden cardiac arrest. Researchers will use a pacing procedure to measure heart wave changes in 400 participants, inc…
Sponsor: Population Health Research Institute • Aim: Diagnosis
Last updated Jul 24, 2026 00:00 UTC
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Simple cheek swab could predict sudden cardiac death risk
Diagnosis Recruiting nowThis study explores whether a quick, painless cheek swab can spot protein changes linked to inherited heart conditions that cause sudden cardiac death in young people. Researchers will collect samples from 26 patients with arrhythmic disorders or family members at risk. If the te…
Sponsor: St. George's Hospital, London • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
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Brazil launches massive heart gene hunt to unlock hereditary mysteries
Knowledge-focused Recruiting nowThis study is building a registry of 1,211 people in Brazil who have inherited heart conditions like cardiomyopathy, arrhythmias, and Marfan syndrome. Researchers will collect DNA samples and medical information to discover which genes are most commonly affected and how often the…
Sponsor: Hospital do Coracao • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC