Breast lobular carcinoma

This study looks at whether giving hormone therapy before breast-conserving surgery helps reduce leftover cancer cells at the edges of removed tissue. It involves 176 postmenopausal women with stage 2-3 ER+/HER2- invasive lobular carcinoma. The goal is to see if this approach lea…

This early-phase study is testing two radioactive imaging agents, 68Ga-DFC413 and 68Ga-NNS309, to see how well they highlight tumors on PET scans. About 66 adults with advanced pancreatic, lung, breast, colorectal, or soft tissue cancers will receive the agents. The goal is to co…

This study tests whether a special PET/MRI scan can accurately detect if breast cancer has spread to lymph nodes in the armpit, potentially replacing the need for surgical removal of those nodes. About 119 women with certain types of breast cancer (luminal A or lobular) will get …

This study compares a new radiation technique called lattice radiation therapy (LRT) to standard stereotactic body radiation therapy (SBRT) for people with solid tumors that have spread to soft tissues. The goal is to see if LRT shrinks tumors better and helps the immune system f…

This study looks back at medical records of 250 people with a rare type of breast cancer called apocrine lobular carcinoma. Researchers want to understand how this cancer behaves, what treatments patients received, and how they did over time. No new treatments are tested — the go…

This study is creating a registry for people with a rare type of breast cancer called invasive lobular carcinoma that has spread. Researchers will collect data from about 12 participants to develop a new tool that better measures how well treatments are working. The goal is to im…

This pilot study is looking for better ways to see if endocrine therapy is working in people with a type of breast cancer called metastatic invasive lobular carcinoma. Researchers will use a special PET scan and blood tests to measure changes in estrogen signaling after 4 weeks o…