Binder syndrome
MONDO:0007953A rare developmental anomaly, affecting primarily the anterior part of the maxilla and nasal complex.
Also known as: Binder syndrome, Maxillonasal dysostosis, binder syndrome, MAXILLONASAL dysplasia, BINDER type, maxillonasal dysplasia
17 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New face mask technique may fix underbite without surgery
Disease control CompletedThis study tested two ways to pull the upper jaw forward in 40 children aged 7-13 with underbite. One method used a traditional face mask attached to teeth, the other used tiny screws placed in the cheekbone. Both followed a special expansion protocol. The goal was to see which a…
Phase: NA • Sponsor: Murat Kaan Erdem • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Gene sequencing uncovers mysterious fetal malformations
Knowledge-focused CompletedThis study tested whether a powerful DNA test called high-throughput exome sequencing can find genetic causes of multiple birth defects in fetuses when standard exams fail. Researchers studied 100 fetuses with at least two malformations and no prior diagnosis. They compared the n…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Speedy gene test aims to give answers on birth defects in just 7 days
Knowledge-focused CompletedThis study tested whether a fast type of genetic test called rapid genome sequencing can find the cause of birth defects seen on ultrasound more quickly than current methods. Researchers included 184 pregnancies with certain ultrasound findings. The goal was to see if results cou…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New study tests if bone punctures help jaw expansion in adults
Knowledge-focused CompletedThis study looked at two methods to widen the upper jaw in adults whose jawbone has fully grown. One method uses small screws anchored in the roof of the mouth, and the other adds tiny bone punctures to help the jaw separate more easily. Twenty-four adults took part, and the resu…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Jaw expansion may improve muscle balance in kids
Knowledge-focused CompletedThis study looked at 34 children with a narrow upper jaw (maxillary hypoplasia) who needed a rapid palatal expander. Researchers measured the electrical activity of chewing muscles before treatment, right after expansion, and 6 months later. The goal was to see if correcting the …
Phase: NA • Sponsor: University of Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC