Beriberi
MONDO:0006676Beriberi is a condition that occurs in people who are deficient in thiamine (vitamin B1). There are two major types of beriberi: wet beriberi which affects the cardiovascular system and dry beriberi which affects the nervous system. People with wet beriberi may experience increased heart rate, shortness of breath, and swelling of the lower legs. Signs and symptoms of dry beriberi include difficulty walking; loss of feeling in the hands and/or feet; paralysis of the lower legs; mental confusion; speech difficulty; pain; and/or vomiting. Beriberi is rare in the United States since many foods are now vitamin enriched; however, alcohol abuse, dialysis and taking high doses of diuretics increases the risk of developing the condition. In most cases,beriberi occurs sporadically in people with no family history of the condition. A rare condition known as genetic beriberi is inherited (passed down through families) and is associated with an inability to absorb thiamine from foods. Treatment generally includes thiamine supplementation, given by injection or taken by mouth.
Also known as: Beri Beri, thiamine deficiency, vitamin B1 deficiency
9 clinical trials for this condition and its sub-types.
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Broader categories
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New scoring system aims to cut child deaths from malnutrition in chad
Disease control CompletedThis study tested a simple scoring system called RISQ to help healthcare workers quickly identify which severely malnourished children are most at risk of dying. Over 14,600 children aged 6 to 59 months in Chad took part. The goal was to see if using the RISQ system could lower d…
Phase: NA • Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can cookies fight malnutrition? new study tests a tasty solution
Disease control CompletedThis study tested whether special cookies made from soy, chickpea, and peanut flour could improve the health of malnourished children. Sixty children aged 3 to 10 years were split into two groups: one group ate the cookies daily for three months along with their regular diet, whi…
Phase: NA • Sponsor: Mairaj Noor • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Vitamin B1 shows promise for Kids' hearts after hole closure
Disease control CompletedThis study looked at whether giving thiamine (vitamin B1) for 28 days after a heart defect repair procedure helps children's hearts recover. The trial included 86 children aged 6 months to 18 years with certain heart defects. Researchers measured heart structure and function usin…
Phase: EARLY_PHASE1 • Sponsor: Universitas Sumatera Utara • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Hidden vitamin shortage: study reveals thiamine deficiency in hospitalized veterans
Knowledge-focused CompletedThis study looked at how often thiamine (vitamin B1) deficiency occurs in hospitalized veterans who do not abuse alcohol. Thiamine deficiency can cause symptoms like fatigue, confusion, and weakness, and may be more common in veterans due to food insecurity and chronic illness. R…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Hidden gut infections may sabotage TB recovery, study suggests
Knowledge-focused CompletedThis completed study looked at 141 people being treated for tuberculosis (TB) to see if intestinal parasites or poor nutrition made their recovery harder. Researchers checked stool samples for parasites and measured weight gain and treatment success. Some participants received nu…
Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC