Babesiosis
MONDO:0005661Babesiosis refers to a condition caused by microscopic parasites that infect the red blood cells. Many people who are infected with Babesia parasites do not experience any symptoms of the condition. When present, signs and symptoms may include flu-like symptoms such as fever, chills, headache, body aches, nausea and fatigue. In severe cases, babesiosis can be associated with hemolytic anemia. Babesia parasites are primarily spread by infected ticks. Treatment is generally only required in people who develop symptoms of the condition. When necessary, affected people are often prescribed a combination of antimicrobial medications along with supportive care to manage symptoms.
Also known as: Babesia caused disease or disorder, Babesia disease or disorder, Babesia infectious disease, babesiasis, infection by Babesia, piroplasmosis, Babesia parasite infection, Human babesiosis
5 clinical trials for this condition and its sub-types.
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NIH opens study to treat parasitic infections like malaria and worms
Disease control Recruiting nowThis study at the National Institutes of Health evaluates and treats people aged 3 and older with known or suspected parasitic infections, such as malaria, intestinal worms, and others. Participants receive standard medical care, not experimental treatments. The goal is to monito…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New drug trial aims to beat exhaustion from Tick-Borne disease
Disease control Recruiting nowThis phase 2 study tests the drug tafenoquine in 40 adults with chronic babesiosis who have severe fatigue. The goal is to see if tafenoquine can reduce fatigue and clear the Babesia parasite from the blood. Participants take the drug and report their fatigue levels using a stand…
Phase: PHASE2 • Sponsor: 60 Degrees Pharmaceuticals LLC • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Experimental drug offers hope for stubborn Tick-Borne infection
Disease control AVAILABLEThis expanded access program provides tafenoquine, an antimalarial drug, to immunocompromised patients with persistent babesiosis (a tick-borne illness) who haven't gotten better with standard treatments. Participants take the drug daily for 4 days, then weekly until they test ne…
Sponsor: 60 Degrees Pharmaceuticals LLC • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Could an antimalarial drug speed recovery from babesiosis?
Disease control Recruiting nowThis study tests whether adding the antimalarial drug tafenoquine to standard care helps hospitalized babesiosis patients recover faster. About 33 adults with confirmed Babesia infection will receive either tafenoquine or a placebo, plus standard antibiotics. Researchers will tra…
Phase: PHASE2 • Sponsor: 60 Degrees Pharmaceuticals LLC • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Tick-Borne mystery: french study aims to uncover hidden cases of babesiosis
Knowledge-focused Recruiting nowThis study looks back at 100 cases of human babesiosis, a rare tick-borne disease, diagnosed in France between 2000 and 2024. Researchers want to describe who gets it, what symptoms they have, and how they are treated. The goal is to improve recognition and care, especially for v…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC