New drug trial aims to beat exhaustion from Tick-Borne disease

NCT ID NCT06656351

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 study tests the drug tafenoquine in 40 adults with chronic babesiosis who have severe fatigue. The goal is to see if tafenoquine can reduce fatigue and clear the Babesia parasite from the blood. Participants take the drug and report their fatigue levels using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
tafenoquine
What this could lead to
If it works, this could provide a treatment option for chronic babesiosis patients suffering from severe fatigue.
What could go wrong
This is a small, early-phase trial with only 40 participants and no placebo group, so results may not be conclusive. The drug may not improve fatigue or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States