Autonomic dysreflexia
MONDO:0043975A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)
Also known as: autonomic dysreflexia, Dysreflexia, autonomic, Dysreflexia, spinal autonomic, Dysreflexias, autonomic, Dysreflexias, spinal autonomic, autonomic Dysreflexia, spinal, autonomic Dysreflexias, autonomic Dysreflexias, spinal
11 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Could a simple spray prevent dangerous blood pressure spikes after spinal injury?
Prevention Not yet recruitingThis phase 2 trial tests whether a nitric oxide spray (glyceryl trinitrate) can prevent dangerous blood pressure spikes during bowel care in people with spinal cord injury. 26 participants will receive either the active spray or a placebo during two at-home bowel care sessions. T…
Phase: PHASE2 • Sponsor: Simon Fraser University • Aim: Prevention
Last updated Jun 27, 2026 12:23 UTC
-
Spinal injury heart risk under the microscope
Knowledge-focused Not yet recruitingThis study looks at whether people with long-term spinal cord injury who also have a condition called autonomic dysreflexia (sudden high blood pressure) have changes in their heart structure. Researchers will use MRI scans to compare two groups: 24 people with high-level injury a…
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC