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Autoinflammatory syndrome

MONDO:0019751

A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease.

207 clinical trials for this condition and its sub-types, 21 tagged with Autoinflammatory syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Syndromic disease (7133) ↑ Rheumatic disorder (1792)

Sub-types of Autoinflammatory syndrome

Sarcoidosis 61 trials · 84 incl. sub-types
8 sub-types
- Pulmonary sarcoidosis 20 trials
- Cardiac sarcoidosis 19 trials
- Blau syndrome 3 trials
- Neurosarcoidosis 2 trials Sub-types →
- Skin sarcoidosis 2 trials
- Löfgren syndrome 0 trials
- Hypercalcemic sarcoidosis 0 trials
- Uveoparotid fever 0 trials
Systemic-onset juvenile idiopathic arthritis 25 trials
Periodic fever syndrome 2 trials · 25 incl. sub-types
3 sub-types
- Hereditary periodic fever syndrome 5 trials · 24 incl. sub-types Sub-types →
- Periodic fever syndrome of childhood 0 trials
- Unexplained periodic fever syndrome 0 trials
Type 1 interferonopathy 4 trials · 21 incl. sub-types
9 sub-types
- Type 1 interferonopathy of childhood 0 trials · 19 incl. sub-types Sub-types →
- TREX1-related type 1 interferonopathy 0 trials · 5 incl. sub-types Sub-types →
- ADAR-related type 1 interferonopathy 0 trials · 1 incl. sub-types Sub-types →
- IFIH1-related type 1 interferonopathy 0 trials Sub-types →
- RNASEH2A-related type 1 interferonopathy 0 trials Sub-types →
- RNASEH2B-related type 1 interferonopathy 0 trials Sub-types →
- RNASEH2C-related type 1 interferonopathy 0 trials Sub-types →
- RNU7-1-related type 1 interferonopathy 0 trials Sub-types →
- SAMHD1-related type 1 interferonopathy 0 trials Sub-types →
Autoinflammatory syndrome of childhood 0 trials · 19 incl. sub-types
1 sub-type
- Type 1 interferonopathy of childhood 0 trials · 19 incl. sub-types Sub-types →
VEXAS syndrome 18 trials
Adult-onset Still disease 12 trials
Pyoderma gangrenosum 10 trials
4 sub-types
- Classic pyoderma gangrenosum 3 trials
- Bullous pyoderma gangrenosum 0 trials
- Pustular pyoderma gangrenosum 0 trials
- Vegetative pyoderma gangrenosum 0 trials
Idiopathic recurrent pericarditis 8 trials
PFAPA syndrome 6 trials
Chronic recurrent multifocal osteomyelitis 3 trials · 4 incl. sub-types
3 sub-types
- Sterile multifocal osteomyelitis with periostitis and pustulosis 2 trials
- Majeed syndrome 0 trials
- Chronic recurrent multifocal osteomyelitis 3 0 trials
SAPHO syndrome 3 trials
Schnitzler syndrome 1 trial
Cherubism 1 trial
1 sub-type
- Al Gazali Khidr Prem Chandran syndrome 0 trials
CEBPE-associated autoinflammation-immunodeficiency-neutrophil dysfunction syndrome 0 trials
F12-associated cold autoinflammatory syndrome 0 trials
PAPASH syndrome 0 trials
Pelger-Huet-like anomaly and episodic fever with abdominal pain 0 trials
SAMD9L-associated autoinflammatory syndrome 0 trials
Sharpin-related autoinflammatory syndrome 0 trials
Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation 0 trials
Autoinflammatory disease, X-linked 0 trials
Autoinflammatory disease, multisystem, with immune dysregulation, X-linked 0 trials
2 sub-types
- Early-onset autoimmune disorder due to DOCK11 partial deficiency 0 trials
- Early-onset immune dysregulation due to DOCK11 complete deficiency 0 trials
Autoinflammatory disease, systemic, with vasculitis 0 trials
Autoinflammatory syndrome with immunodeficiency 0 trials
Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis 0 trials
Autoinflammatory syndrome, familial, Behcet-like 0 trials
2 sub-types
- Autoinflammatory syndrome, familial, Behcet-like 1 0 trials
- Autoinflammatory syndrome, familial, X-linked, Behcet-like 2 0 trials
Autoinflammatory syndrome due to TBK1 deficiency 0 trials
Early-onset pulmonary and cutaneous vasculitis 0 trials
Granulomatous autoinflammatory syndrome of childhood 0 trials
Infantile onset panniculitis with uveitis and systemic granulomatosis 0 trials
Magic syndrome 0 trials
Neonatal inflammatory skin and bowel disease 0 trials
2 sub-types
- Inflammatory skin and bowel disease, neonatal, 1 0 trials
- Inflammatory skin and bowel disease, neonatal, 2 0 trials
Neonatal-onset severe multisystemic autoinflammatory disease with increased IL18 0 trials
Psoriasis 14, pustular 0 trials
Pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 0 trials
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome 0 trials

Most studied deeper sub-types

Familial Mediterranean fever (15) Cryopyrin-associated periodic syndrome (10) Aicardi-Goutieres syndrome (9) CINCA syndrome (4) TNF receptor 1-associated periodic fever syndrome (4) Autoimmune interstitial lung disease-arthritis syndrome (3) Deficiency of adenosine deaminase 2 (3) Familial cold autoinflammatory syndrome (3) Mevalonate kinase deficiency (3) Muckle-Wells syndrome (3) Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (3) Aicardi-Goutieres syndrome 1 (2) Familial chilblain lupus (2) Hyperimmunoglobulinemia D with periodic fever (2) Periodic fever-infantile enterocolitis-autoinflammatory syndrome (2) Proteosome-associated autoinflammatory syndrome (2) STING-associated vasculopathy with onset in infancy (2) Cerebral sarcoidosis (1) Dyschromatosis symmetrica hereditaria (1) Proteasome-associated autoinflammatory syndrome 1 (1)

Including sub-types (207) Tagged with Autoinflammatory syndrome (21)

Trials to join now! 12 Not yet recruiting 4 Completed 5

Autoinflammatory syndrome

Where it sits in the disease tree

Most studied deeper sub-types

NIH launches major study to unlock secrets of rare inflammatory diseases

Massive study reveals COVID-19 risks for autoimmune patients

Scientists probe genetic roots of Cold-Triggered hives

Coaching eases tough move to adult rheumatology care

New blood tests could help monitor Flare-Ups in kids with arthritis