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Atopic IgE-mediated allergic disorder
MONDO:0005202A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.
Also known as: Atopic allergy, atopic state, atopy
25 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New eczema drug shows promise in Mid-Stage trial
Disease control OngoingThis study tests whether ATI-045 can safely reduce eczema symptoms like redness, itching, and skin patches in people with moderate-to-severe disease. About 110 adults who haven't had success with topical treatments will receive either the drug or a placebo. The main goal is to se…
Phase: PHASE2 • Sponsor: Aclaris Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New allergy shot for teens shows early promise
Symptom relief OngoingThis study tests a new injection called LP-003 in 6 teenagers aged 12 to 18 who have allergies like hay fever, asthma, or eczema. The main goal is to check if the drug is safe and how the body processes it. This is an early-stage trial, so it focuses on safety and drug levels rat…
Phase: PHASE1, PHASE2 • Sponsor: Longbio Pharma • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Breast Milk's hidden clues: could MicroRNAs predict baby allergies?
Knowledge-focused OngoingThis study followed 221 breastfeeding mothers and their babies to see if small molecules called microRNAs in breast milk are linked to allergies, eczema, or wheezing in the first year of life. Researchers measured these molecules in milk samples and tracked babies' health. The go…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC