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Atopic IgE-mediated allergic disorder
MONDO:0005202A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.
Also known as: Atopic allergy, atopic state, atopy
25 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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HPV vaccine shows promise for girls on Immune-Suppressing drugs
⭐️ VACCINE ⭐️ CompletedThis study looked at whether the HPV vaccine works in girls aged 9 to 17 who are taking medicines that weaken their immune system, such as after an organ transplant or for diseases like lupus. The goal was to see if their bodies produce enough antibodies to protect against HPV. T…
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:36 UTC
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New drug camoteskimab tested for Tough-to-Treat eczema
Disease control CompletedThis study tested a new drug, camoteskimab, in 62 adults with moderate to severe eczema (atopic dermatitis). Participants received either the drug or a placebo for 16 weeks, followed by an open-label extension where everyone could get the drug. The main goal was to see if camotes…
Phase: PHASE2 • Sponsor: Apollo Therapeutics Ltd • Aim: Disease control
Last updated Jun 26, 2026 17:44 UTC
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Special formula may shield At-Risk babies from allergies
Prevention CompletedThis study tested whether a low-protein, extensively hydrolyzed infant formula with added pre- and probiotics can prevent allergies in babies at high risk. Over 1,200 healthy newborns were given either the special formula or a standard formula during their first months of life. R…
Phase: NA • Sponsor: HiPP GmbH & Co. Vertrieb KG • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Can a spruce extract cream soothe sensitive skin? new study says maybe.
Symptom relief CompletedThis study tested whether a cream made with spruce tree extract can help repair the skin barrier and reduce symptoms like dryness, redness, and itching in people with sensitive, atopy-prone skin. 66 healthy adults used the cream or a placebo for 21 days. Researchers measured skin…
Phase: NA • Sponsor: Repolar Pharmaceuticals Oy • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New pill for Kids' eczema itch shows promise in large trial
Symptom relief CompletedThis study tested whether a new oral medicine called TAU-284 (bepotastine besilate) can reduce itching in children aged 7 to 15 with atopic dermatitis (eczema). Over 300 children took either TAU-284 or an older medicine (ketotifen) twice daily for several weeks. The main goal was…
Phase: PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Scientists gather clues on mysterious immune defects
Knowledge-focused CompletedThis study collected blood, saliva, stool, urine, and skin samples from 19 people with unknown or poorly understood immune system problems. The goal was to learn how different parts of the immune system work together. No treatments or drugs were tested. Participants were followed…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Could a simple drink before pregnancy shape your child's future health?
Knowledge-focused CompletedThis study followed 461 children whose mothers took a special nutritional drink before and during pregnancy. Researchers want to understand how parents' diet, lifestyle, and metabolism influence child growth, thinking skills, and overall well-being. The goal is to identify factor…
Phase: NA • Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC