Atopic IgE-mediated allergic disorder
MONDO:0005202A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.
Also known as: Atopic allergy, atopic state, atopy
20 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Needle-Free epinephrine film could transform emergency allergy care for kids
Disease control CompletedThis study tests a new dissolving film called DESF that delivers epinephrine under the tongue. It is designed for children ages 7 to 17 who weigh at least 30 kg and have a history of allergic reactions that put them at high risk for severe episodes like anaphylaxis. The goal is t…
Phase: PHASE1 • Sponsor: Aquestive Therapeutics • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New drug camoteskimab tested for Tough-to-Treat eczema
Disease control CompletedThis study tested a new drug, camoteskimab, in 62 adults with moderate to severe eczema (atopic dermatitis). Participants received either the drug or a placebo for 16 weeks, followed by an open-label extension where everyone could get the drug. The main goal was to see if camotes…
Phase: PHASE2 • Sponsor: Apollo Therapeutics Ltd • Aim: Disease control
Last updated Jun 26, 2026 17:44 UTC
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Special formula may shield At-Risk babies from allergies
Prevention CompletedThis study tested whether a low-protein, extensively hydrolyzed infant formula with added pre- and probiotics can prevent allergies in babies at high risk. Over 1,200 healthy newborns were given either the special formula or a standard formula during their first months of life. R…
Phase: NA • Sponsor: HiPP GmbH & Co. Vertrieb KG • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Can a spruce extract cream soothe sensitive skin? new study says maybe.
Symptom relief CompletedThis study tested whether a cream made with spruce tree extract can help repair the skin barrier and reduce symptoms like dryness, redness, and itching in people with sensitive, atopy-prone skin. 66 healthy adults used the cream or a placebo for 21 days. Researchers measured skin…
Phase: NA • Sponsor: Repolar Pharmaceuticals Oy • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New pill for Kids' eczema itch shows promise in large trial
Symptom relief CompletedThis study tested whether a new oral medicine called TAU-284 (bepotastine besilate) can reduce itching in children aged 7 to 15 with atopic dermatitis (eczema). Over 300 children took either TAU-284 or an older medicine (ketotifen) twice daily for several weeks. The main goal was…
Phase: PHASE3 • Sponsor: Tanabe Pharma Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Could a simple drink before pregnancy shape your child's future health?
Knowledge-focused CompletedThis study followed 461 children whose mothers took a special nutritional drink before and during pregnancy. Researchers want to understand how parents' diet, lifestyle, and metabolism influence child growth, thinking skills, and overall well-being. The goal is to identify factor…
Phase: NA • Sponsor: University of Southampton • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC