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Aspergillosis

MONDO:0005657

Aspergillosis is an infection, growth, or allergic response caused by the Aspergillus fungus. There are several different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA), a condition where the fungus causes allergic respiratory symptoms similar to asthma, such as wheezing and coughing, but does not actually invade and destroy tissue. Another kind of aspergillosis is invasive aspergillosis. This infection usually affects people with weakened immune systems due to cancer, AIDS, leukemia, organ transplantation, chemotherapy, or other conditions or events that reduce the number of normal white blood cells. In this condition, the fungus invades and damages tissues in the body. Invasive aspergillosis most commonly affects the lungs, but can also cause infection in many other organs and can spread throughout the body (commonly affecting the kidneys and brain). Aspergilloma, a growth (fungus ball) that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third kind of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball gradually enlarges, destroying lung tissue in the process, but usually does not spread to other areas.

51 clinical trials for this condition and its sub-types.

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Sub-types

Invasive aspergillosis (30) Allergic bronchopulmonary aspergillosis (13) Pulmonary aspergilloma (8) Aspergillus niger infection (0) Malt worker's lung (0) Neuroaspergillosis (0)

Broader categories

Disease (680) Infectious disease (282) Fungal infectious disease (36) Human disease (14) Disease by etiologic mechanism (0) Disease of primarily extrinsic mechanism (0) Opportunistic mycosis (0)
Trials to join now! 23 Not yet recruiting 7 Not yet finished but already full! 4 Completed 15 Terminated 2
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