Ascariasis
MONDO:0005654An infection that is caused by the roundworm Ascaris lumbricoides, many cases of which remain asymptomatic. During the transient larval migratory phase, shortness of breath, fever, and eosinophilia can occur. Depending on the intestinal worm burden, a spectrum of gastrointestinal tract symptoms can occur.
Also known as: Ascaris lumbricoides caused disease or disorder, Ascaris lumbricoides disease or disorder, Ascaris lumbricoides infectious disease
11 clinical trials for this condition and its sub-types, 10 tagged with Ascariasis itself.
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One pill to beat worms? new drug emodepside takes on mebendazole
Disease control CompletedThis phase 3 trial tests whether a single dose of emodepside can cure soil-transmitted worm infections (like whipworm, hookworm, and roundworm) better than the standard 3-day course of mebendazole. About 315 adolescents and adults with confirmed infections will receive either emo…
Phase 3 • Sponsor: Swiss Tropical & Public Health Institute • Aim: Disease control
Last updated Oct 10, 2026 00:00 UTC
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New combo drug doses aim to wipe out whipworm in toddlers
Disease control CompletedThis study tested whether higher doses of ivermectin, combined with albendazole, are safe and effective for treating whipworm infections in children aged 2 to 5 years. The trial involved 260 children in Tanzania and compared different doses of ivermectin, including a new dissolva…
Phase 2 • Sponsor: Jennifer Keiser • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could a Two-Drug punch finally knock out whipworm in kids?
Disease control CompletedThis study tested whether combining two drugs—moxidectin and albendazole—works better than albendazole alone for treating whipworm infections in children aged 6 to 12. The trial took place in Tanzania and involved 224 children. Researchers measured how many children were cured an…
Phase 3 • Sponsor: Jennifer Keiser • Aim: Disease control
Last updated Jun 26, 2026 19:06 UTC