Appendix adenocarcinoma
MONDO:0006087A carcinoma that arises from glandular epithelial cells of the vermiform appendix.
Also known as: adenocarcinoma of appendix, adenocarcinoma of the appendix, appendiceal adenocarcinoma, appendix adenocarcinoma, vermiform appendix adenocarcinoma, APAD
2925 clinical trials for this condition and its sub-types, 12 tagged with Appendix adenocarcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Appendix adenocarcinoma
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Mucinous adenocarcinoma of the appendix 4 trials · 19 incl. sub-types
2 sub-types
- Pseudomyxoma peritonei 17 trials
- Appendix mucinous cystadenocarcinoma 0 trials
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Can Direct-to-Abdomen chemotherapy tame GI cancers that spread?
Disease control Recruiting nowThis phase II trial tests whether adding paclitaxel directly into the abdomen, alongside standard systemic chemotherapy, is feasible for people with gastrointestinal cancers that have spread to the peritoneal lining. The study includes patients with gastric, colorectal, appendice…
Phase 2 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Experimental shot takes aim at stomach cancer spread
Disease control Recruiting nowThis early-stage trial tests a drug called ACM-CpG, which is injected directly into the abdomen to stimulate the immune system against cancer. It includes 24 adults with colorectal or appendix cancer that has spread to the lining of the abdomen or caused fluid buildup. The main g…
Phase 1 • Sponsor: Brown University • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Supercharged t cells take on Hard-to-Treat cancers
Disease control Expanded accessThis treatment program tests a personalized cell therapy for people with advanced pancreatic or colorectal cancers that have a specific genetic mutation (KRAS G12D). Patients' own immune cells are collected, genetically engineered to recognize and attack the cancer, and then infu…
Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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New hope for rare appendix cancer: targeted chemotherapy delivered straight to the belly
Disease control Recruiting nowThis study tests a chemotherapy drug called paclitaxel, given directly into the abdominal cavity, for people with appendix cancer that has spread. The goal is to find a safe dose and see if it helps control the disease. About 39 adults with advanced appendix cancer that cannot be…
Phase 1/2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Blood test could personalize chemo for gut cancer patients
Disease control Recruiting nowThis study is testing whether a simple blood test that measures tumor DNA (ctDNA) can help doctors decide how much chemotherapy to give before surgery for colorectal or appendix cancer that has spread to the abdomen. The goal is to see if the test can identify patients who need s…
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Glowing dye could help surgeons spot hidden cancers during surgery
Diagnosis Recruiting nowThis study tests whether a dye called pafolacianine (CYTALUX™) can make cancer cells glow under near-infrared light during surgery. Fifteen adults with gastric, esophageal, or appendiceal cancer will receive the dye before standard surgery. Surgeons will use a special camera to l…
Phase 4 • Sponsor: Cedars-Sinai Medical Center • Aim: Diagnosis
Last updated Jun 26, 2026 17:19 UTC
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Personalized chemo test aims to improve treatment for advanced abdominal cancers
Knowledge-focused Recruiting nowThis study tests a new method called mass-based response testing (MRT) to help doctors choose the best chemotherapy drugs for patients with advanced appendix or colorectal cancer that has spread to the abdomen. The MRT device analyzes live tumor cells to see which drugs work best…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Scientists dig into DNA of rare gut cancer to improve prognosis
Knowledge-focused Recruiting nowThis study looks at stored tumor samples from 400 people with appendiceal cancer. Researchers will analyze DNA and RNA modifications to find patterns linked to how the cancer behaves. The goal is to create a molecular score that could one day help doctors predict outcomes more ac…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC