Experimental shot takes aim at stomach cancer spread
NCT ID NCT07658196
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests a drug called ACM-CpG, which is injected directly into the abdomen to stimulate the immune system against cancer. It includes 24 adults with colorectal or appendix cancer that has spread to the lining of the abdomen or caused fluid buildup. The main goal is to find a safe dose and see if it helps control the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ACM-CpG (a drug that stimulates the immune system)
- What this could lead to
- If it works, this could point toward a new treatment option for cancers that have spread to the abdomen.
- What could go wrong
- This is a very early phase 1 trial with only 24 people, so it is mainly checking safety and dosing. The drug may not shrink tumors or improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for APPENDICEAL ADENOCARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rhode Island and the Miriam Hospitals (Brown University Health)
Providence, Rhode Island, 02903/02906, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Double-Targeted cell therapy outsmart Cancer's hideouts?
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can a new immunotherapy combo tame aggressive appendiceal cancer?
- Can a new immunotherapy combo shrink Hard-to-Treat tumors?
- Breath of life: new test could sniff out gut cancers before they spread
- Gut instinct: listening to bowel sounds may reveal hidden clues about surgical recovery