Antisocial personality disorder
MONDO:0001164A disorder characterized by a pervasive pattern of disregard for and violation of the rights of others that is manifested in childhood or early adolescence. (adapted from DSM-IV)
Also known as: Sociopathy, asocial personality, dissocial personality disorder, psychopathic personality, psychopathic personality disorder, psychopathy, sociopathic personality
53 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can a smartphone app help curb teen aggression? new study says maybe.
Disease control OngoingThis study compares a new blended therapy (online sessions plus in-person visits) to standard in-person therapy for teens with conduct disorder or antisocial behavior. Researchers want to see if the blended approach works just as well at reducing aggression, delinquency, and out-…
Phase: NA • Sponsor: Utrecht University • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Drugs and therapy together: a new hope for anxiety, depression, and more?
Disease control OngoingThis early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…
Phase: PHASE1 • Sponsor: Rakitzi, Stavroula • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Could home therapy replace hospital stays for kids with mental health issues?
Disease control OngoingThis study tests whether intensive home-based psychiatric treatment can help children and teens with mental health disorders as an alternative to being in the hospital. Over 3 months, participants receive 3 to 7 home visits per week from a team of doctors, therapists, and other s…
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Can rewriting your life story improve mental health? small trial tests new therapy
Symptom relief OngoingThis study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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New program aims to heal war trauma passed down in refugee families
Symptom relief OngoingThis study tests a program that combines family group sessions with a virtual peer mentoring program for US-born teens (ages 14-17) whose parents resettled as refugees. The goal is to reduce symptoms of PTSD, depression, anxiety, and behavior problems caused by intergenerational …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can acting out help heal? drama therapy trial targets dual diagnosis
Symptom relief TerminatedThis pilot study tests a specific type of drama therapy for people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks, then put on a performance.…
Phase: NA • Sponsor: Boston Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Can a 'Courage and Love' group therapy beat loneliness in seniors?
Symptom relief OngoingThis study tests a group therapy called Awareness, Courage, and Love (ACL) for older adults with psychiatric disorders who feel lonely. The therapy focuses on mindfulness, sharing feelings, and building connections. Researchers want to see if the program is practical and helpful …
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Can online therapy plus In-Person sessions help personality disorders?
Symptom relief OngoingThis study is testing a new type of therapy called Blended Dynamic Interpersonal Therapy (B-DIT) for adults with personality disorders. The therapy mixes face-to-face sessions with online modules over several months. The goal is to see if this approach is acceptable to patients a…
Sponsor: De Viersprong • Aim: Symptom relief
Last updated Jun 26, 2026 15:50 UTC
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Can peers help people recover from mental illness? new study says maybe
Knowledge-focused OngoingThis study tests a 10-week program called 'Grow to Recovery' for people with mental illness. The program is co-led by a peer (someone who also has a mental illness) and a professional. Researchers want to see if it helps participants feel more hopeful and capable. 138 people are …
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Ottawa study aims to help homeless youth cut back on tobacco and drugs
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at tobacco, cannabis, and other drug use among homeless and at-risk youth in downtown Ottawa. Researchers will follow 520 participants aged 16 and older who are homeless or insecurely housed and have a history of cannabis use and mental illness. The goal is to un…
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Real-World therapy study seeks to unlock secrets of personality disorder treatment
Knowledge-focused OngoingThis study follows 91 adults with personality disorders who are receiving intensive psychodynamic therapy in a real-world clinic. Researchers want to see if the therapy works as well outside of strict research settings and what specific factors lead to improvement. The goal is to…
Sponsor: KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Which therapy works best for troubled teens? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC