ACTH-independent Cushing syndrome
MONDO:0020529A group of endogenous Cushing syndrome that may result from excess secretion of cortisol by either a unilateral and benign, or malignant adrenocortical tumor, or nodular adrenocortical disease.
Also known as: adrenal Cushing syndrome, adrenocorticotropic hormone-independent Cushing syndrome, corticotropin-independent Cushing syndrome
19 clinical trials for this condition and its sub-types.
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Broader categories
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Can a drug tame excess cortisol? new trial tests metyrapone
Disease control OngoingThis phase 2 trial tests whether metyrapone, a drug that lowers cortisol production, is safe and effective for people with mild autonomous cortisol secretion (MACS). About 30 participants will take the drug for a period, and researchers will track side effects and cortisol levels…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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AI could help detect Kids' coordination problems earlier
Diagnosis OngoingThis study is testing a new AI-based system called AIMAS that aims to assess motor skills in children aged 6 to 12. The goal is to see if the AI can reliably identify kids with developmental coordination disorder (DCD) compared to standard clinical methods. Researchers will enrol…
Sponsor: Chang Gung Memorial Hospital • Aim: Diagnosis
Last updated Jun 26, 2026 14:23 UTC
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Brain scans reveal hidden links between body diseases and metabolism
Knowledge-focused OngoingThis study watches 200 people with lung, gut, or hormone diseases over time using special brain scans (PET). It aims to see how these diseases change brain activity and whether those changes can predict tumor return, spread, or survival. No new treatment is tested—just observatio…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC