Acquired thrombotic thrombocytopenic purpura
MONDO:0019740Acquired thrombotic thrombocytopenic purpura is the non-hereditary form of thrombotic thrombocytopenic purpura (TTP), characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity.
Also known as: TTP, purpura, thrombotic thrombocytopenic, acquired ADAMTS13 deficiency, acquired TTP, acquired thrombotic thrombocytopenic purpura, autoimmune thrombotic thrombocytopenic purpura, Moschowitz syndrome, idiopathic thrombotic thrombocytopenic purpura
65 clinical trials for this condition and its sub-types.
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Tailored drug regimen shows promise for rare blood disorder
Disease control TerminatedThis study tested whether giving the drug caplacizumab based on regular blood tests (ADAMTS13 activity) could improve outcomes for adults with acquired thrombotic thrombocytopenic purpura (aTTP), a rare condition causing dangerous blood clots. The trial enrolled 58 adults and mon…
Phase: PHASE2 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Can extra care after transplant help older patients live better?
Disease control TerminatedThis study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…
Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC