Acquired thrombotic thrombocytopenic purpura
MONDO:0019740Acquired thrombotic thrombocytopenic purpura is the non-hereditary form of thrombotic thrombocytopenic purpura (TTP), characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity.
Also known as: TTP, purpura, thrombotic thrombocytopenic, acquired ADAMTS13 deficiency, acquired TTP, acquired thrombotic thrombocytopenic purpura, autoimmune thrombotic thrombocytopenic purpura, Moschowitz syndrome, idiopathic thrombotic thrombocytopenic purpura
25 clinical trials for this condition and its sub-types.
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Real-world study examines caplacizumab for aTTP: better treatment on the horizon?
Disease control OngoingThis study looks back at how doctors in Germany prescribed caplacizumab (Cablivi) for acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood clotting disorder. Researchers will analyze data from 350 patients to see how well the drug works outside of clinical trials and…
Sponsor: University of Cologne • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New rapid test could speed up diagnosis of deadly blood clotting disorder
Diagnosis OngoingThis study is testing a new, faster blood test for diagnosing acquired thrombotic thrombocytopenic purpura (aTTP), a rare but life-threatening blood clotting disorder. The new test, called HemosIL AcuStar, will be compared to two existing tests in 500 patients from Spain and Port…
Sponsor: Fundación Española de Hematología y Hemoterapía • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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AI takes on blood clotting: can ChatGPT guide surgeons on bleeding?
Knowledge-focused TerminatedThis study evaluates whether artificial intelligence models can accurately interpret ROTEM blood clotting tests and recommend treatments for coagulopathy. Researchers will compare AI decisions to those of a panel of clinical experts using data from adults undergoing elective card…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC