New rapid test could speed up diagnosis of deadly blood clotting disorder

NCT ID NCT05046717

First seen Feb 17, 2026 · Last updated Jun 20, 2026 · Updated 18 times

Summary

This study is testing a new, faster blood test for diagnosing acquired thrombotic thrombocytopenic purpura (aTTP), a rare but life-threatening blood clotting disorder. The new test, called HemosIL AcuStar, will be compared to two existing tests in 500 patients from Spain and Portugal. The goal is to see if it can diagnose severe ADAMTS13 deficiency more quickly and accurately, which could help doctors start life-saving treatment sooner.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centro Hospitalar e Universitario de Coimbra

    Coimbra, Coimbra District, 3004-561, Portugal

  • Complejo Hospitalario Universitario A Coruña

    A Coruña, A Coruña, 15006, Spain

  • Hospital Clinic de Barcelona

    Barcelona, Spain

  • Hospital Clínico San Carlos

    Madrid, Spain

  • Hospital Gregorio Marañon

    Madrid, Spain

  • Hospital La Fe de Valencia

    Valencia, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ADAMTS13 activity test (HemosIL AcuStar chemiluminescent assay)

What this could lead to

If successful, this could lead to faster and more accurate diagnosis of TTP, helping doctors start the right treatment sooner and potentially saving lives.

What could go wrong

This is a diagnostic validation study, not a treatment trial. The new test may not prove significantly better than existing methods, and results may not apply to all populations.

Conditions

The condition(s) this trial relates to.

thrombotic thrombocytopenic purpura

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.