Tailored drug regimen shows promise for rare blood disorder
NCT ID NCT04720261
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving the drug caplacizumab based on regular blood tests (ADAMTS13 activity) could improve outcomes for adults with acquired thrombotic thrombocytopenic purpura (aTTP), a rare condition causing dangerous blood clots. The trial enrolled 58 adults and monitored for death, lack of response, or worsening disease within 30 days. The goal was to see if a personalized approach could reduce complications while using the drug more efficiently.
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ah-Hp Hopital Saint Louis
Paris, 75010, France
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Ap-Hm Hopital de La Conception
Marseille, 13005, France
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Ap-Hp Hopital de Cochin
Paris, 75014, France
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Ap-Hp Hopital de Necker
Paris, 75015, France
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Ap-Hp Hopital de St Antoine
Paris, 75571, France
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CHU CAEN
Caen, 14033, France
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Ch Edouard Herriot
Lyon, 69003, France
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Ch Valenciennes
Valenciennes, 59300, France
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Chu Amiens
Amiens, 80054, France
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Chu Angers
Angers, 49933, France
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Chu Besancon
Besançon, 25030, France
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Chu Bordeaux
Bordeaux, 33404, France
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Chu Clermont-Ferrand
Clermont-Ferrand, 63003, France
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Chu Lille
Lille, 59037, France
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Chu Limoges
Limoges, 87042, France
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Chu Montpellier
Montpellier, 34295, France
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Chu Nancy
Nancy, 54035, France
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Chu Nantes
Nantes, 44093, France
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Chu Reims
Reims, 51092, France
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Chu Rennes
Rennes, 35033, France
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Chu Rouen
Rouen, 76031, France
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Chu Tours
Tours, 37044, France
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Fort de France
Fort-de-France, 97261, Martinique
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Reunion Sud
Saint-Paul, 97448, France