Acquired aneurysmal subarachnoid hemorrhage
MONDO:0019543A serious, life threatening rare neurologic disease characterized by a sudden rupture of an intracranial aneurysm into the subarachnoid space. It usually presents with a sudden, severe, excruciating headache accompanied by nausea, vomiting and syncope. Other features may include focal neurological signs, third and sixth nerve palsies, seizures and cardiac failure. Early complications include rebleeding, hydrocephalus, and seizures.
249 clinical trials for this condition and its sub-types.
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Brain bleed study halted: sodium Lactate's promise unproven
Disease control TerminatedThis study aimed to see if sodium lactate could improve blood flow in the brain after a severe type of stroke called subarachnoid hemorrhage. Only 3 patients were enrolled before the study was stopped early. The goal was to measure changes in brain blood flow using a special scan…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Brain aneurysm device study halted early
Disease control TerminatedThis study looked at a device called the Pipeline Flex Embolization Device with Shield Technology to treat ruptured brain aneurysms that are hard to fix with surgery or coils. The goal was to see if it could safely block the aneurysm and prevent rebleeding. The study was stopped …
Phase: NA • Sponsor: Medtronic Neurovascular Clinical Affairs • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC