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127005 trials found · Page 6271 of 6351
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New diabetes drug candidate tested in healthy people
Knowledge-focused CompletedThe purpose of this study is to compare the pharmacodynamic profile of a single subcutaneous dose of SHR-3167 injection versus insulin glargine U100 in healthy subjects.
Phase 1 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Can you take this allergy pill without water? new study investigates
Knowledge-focused CompletedThe purpose of the study is to assess the relative bioavailability of a new galenic form of fexofenadine HCl new formulation tablet (test drug) taken with or without water compared to fexofenadine HCl film-coated tablets (reference form) taken with water under fasting conditions.
Phase 1 • Sponsor: Opella Healthcare Group SAS, a Sanofi Company • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:50 UTC
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Tiny trial of infant blood pressure cuff ends early
Knowledge-focused Stopped earlyAutomated blood pressure cuff measurements taken by an "oscillometric device" is the standard in numerous medical settings today. Studies show that oscillometric devices using algorithms are more accurate and consistent than devices using other non-invasive measuring techniques,…
Sponsor: Welch Allyn • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Healthy volunteers test new drug ABSK061 in Early-Stage safety study
Knowledge-focused CompletedThe main objective of which is to evaluate the relative bioavailability and PK characteristics of new and old ABSK-011 capsules in a single oral dose
Phase 1 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Smartwatch study for spastic foot surgery stalls after just 2 patients
Symptom relief Stopped earlyPEPS is a 18 months prospective bicentric study on 30 patients with spastic foot. The main objective is to evaluate the mean daily gait perimeter modifications mesured by connected watch, 6 months after spastic equinus foot surgery versus before this surgery. Investigator will le…
Sponsor: University Hospital, Angers • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New drug AG-181 tested in healthy people for first time
Knowledge-focused CompletedThe primary purpose of this study is to assess the safety and tolerability of AG-181 in healthy participants after oral administration of single ascending dose (SAD) of AG-181 in Part 1 and multiple ascending dose (MAD) in Part 2 along with the effect of food on the pharmacokinet…
Phase 1 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New drug SUL-238 put to the test in healthy volunteers
Knowledge-focused CompletedThe goal of this randomized, double-blind, placebo-controlled, single-center study is to evaluate the safety, tolerability, pharmacokinetics of single and multiple oral doses of SUL-238 in healthy subjects (aged ≥40 years).
Phase 1 • Sponsor: GEN İlaç ve Sağlık Ürünleri A.Ş. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Breath test reveals how men of different ages digest protein from everyday foods
Knowledge-focused CompletedThe main goal of this study is to determine the metabolic availability of methionine in black beans, lysine in sorghum and lysine in milk using the indicator amino acid oxidation method both in older and in younger men.
Sponsor: Wageningen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Promising scan study for endometrial cancer pulled before it started
Knowledge-focused CancelledPurpose: The purpose of this study is to evaluate FFNP PET/MRI's utility for predicting response to Levonorgestrel-releasing Intrauterine Device (LR-IUD) hormonal therapy for Complex Atypical hyperplasia (CAH) and Endometrial Cancer (EC). Participants: Eight women with histologi…
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Healthy volunteers test new injection method for eczema drug
Knowledge-focused CompletedThe primary objective of the study is to evaluate the pharmacokinetics (PK) of rocatinlimab given as a single subcutaneous (SC) dose in a vial compared to a prefilled syringe in healthy participants.
Phase 1 • Sponsor: Amgen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Scientists map Brain's speech control in healthy volunteers
Knowledge-focused Recruiting nowThe purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to perceive their own speech errors and to learn new speech …
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Blanket showdown: which warming system wins?
Knowledge-focused CompletedThe investigators propose a single-center multiple crossover randomized trial to determine the efficacy of four warming devices and five warming blankets. The investigators will measure cutaneous heat loss/ gain using thermal flux transducers in unanesthetized volunteers.
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New pulse oximeter put to the test in Low-Oxygen study
Knowledge-focused CompletedThe verification of an investigational pulse oximetry board to verify pulse rate and saturation accuracy over a specified saturation range in diverse populations.
Sponsor: Medtronic - MITG • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Carob drink study: do good chemicals reach your blood?
Knowledge-focused CompletedThis is an interventional, open-label, single-group, bioavailability postprandial study. The aim of the study is to evaluate the bioavailability of phenolic compounds of a beverage prepared with Cretan carob powder of the Imera cultivar in healthy individuals after consumption.
Sponsor: Harokopio University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New eye drop combo tested for safety in healthy people
Knowledge-focused CompletedThis is a phase I study evaluating safety and tolerability through the incidence of unexpected adverse events and IOP measurement, as well as through the incidence of stinging after its administration, compared to placebo.
Phase 1 • Sponsor: Laboratorios Sophia S.A de C.V. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Heated tobacco products put to the test against cigarettes and gum
Knowledge-focused CompletedThis is a randomized, controlled, six-way crossover clinical study to characterize the nicotine PK (pharmacokinetic) and subjective effects of HTPs (Heated Tobacco Products) comprised of 2 menthol varieties and 2 tobacco flavor varieties (Ploom® HTPs, Japan Tobacco Inc.) in adult…
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Cuff training vs. heavy weights: which builds arm strength better?
Knowledge-focused CompletedThis study investigated the effects of low-load resistance training combined with blood flow restriction (BFRT) compared to traditional high-load resistance training on arm muscle strength and isokinetic contraction parameters in healthy young adults. Participants were prospectiv…
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists map normal knee temperatures in healthy young adults
Knowledge-focused CompletedThe Thermo-Young study is a a cross-sectional observational study of healthy volunteers of both sexes. This study aims to assess the temperature of various areas of the knee using thermographic imaging. The aim of the study is to analyze thermographic images of the knees of healt…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Heart valve study pulled before it even started
Disease control CancelledThis study is to evaluate the safety and technical performance of the Cardiovalve Transfemoral System for tricuspid valve replacement. Data collected in the clinical study will include 30-day safety and performance of the device and delivery system, and long-term clinical outcome…
Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Online fracture care study pulled before it began
Knowledge-focused CancelledThe purpose of this study is to compare web FLS model (e\_FLS) to conventional FLS in terms of increasing the proportion of patients receiving an antiosteoporotic treatment in the year after a low trauma fracture.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC