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127005 trials found · Page 6269 of 6351
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Why do pregnant women refuse to join a pre-eclampsia trial? new study investigates.
Knowledge-focused CompletedThe main objective is to assess whether there are factors associated with women's refusal to participate in a randomized clinical trial involving first-trimester screening for pre-eclampsia. The secondary objective is to qualitatively evaluate the reasons for acceptance and refus…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:22 UTC
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Kangaroo care: bonding boost or bust?
Knowledge-focused Stopped earlyThe Kangaroo Unit (UK) takes care of newborns requiring special care or monitoring for a pathology whose clinical situation is stable and whose prognosis is favorable. In order to avoid separating mother and child, these units were created with a care pathway somewhere between th…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New anesthesia drug checked for heart risks in healthy volunteers
Knowledge-focused CompletedTo assess the effects of a single IV bolus of HSK3486 single dose on cardiac repolarization (QTc interval of the electrocardiogram, and to evaluate the safety and tolerability of a single IV bolus of HSK3486 in healthy subjects
Phase 1 • Sponsor: Haisco-USA Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Ashwagandha safety check in seniors: small study ends early
Knowledge-focused Stopped earlyThis study will measure the oral bioavailability and pharmacokinetics of known compounds from a standardized Withania somnifera botanical dietary supplement in healthy older adults.
Early phase 1 • Sponsor: Oregon Health and Science University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New drug PORT-77 tested in humans for first time
Knowledge-focused CompletedA First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation of the administration of PORT-77 in healthy adult participants.
Phase 1 • Sponsor: Portal Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Heart drug study cancelled before it began
Knowledge-focused CancelledCardiovascular disease (CVD) represents the leading cause of death worldwide. While medications, such as statins, significantly reduce atherosclerotic CVD (ASCVD) risk by lowering low density lipoprotein levels, they may also have pleiotropic effects on inflammation. The immunomo…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Promising ITP drug trial pulled before it even started
Disease control CancelledThis is an open-label, multicenter study to evaluate the safety, tolerability, and efficacy of HMPL-523 in adult subjects with ITP.
Phase 1 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 26, 2026 18:23 UTC
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Baby massage class boosts student Know-How, study finds
Knowledge-focused CompletedThe goal of this clinical trial was to learn whether baby massage training could improve midwifery students' knowledge about baby massage. The study focused on students in their third and fourth years who had already completed child health and neonatal care courses. The main que…
Sponsor: Ataturk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Tiny cancer study halted after just one patient
Knowledge-focused Stopped earlyThis phase I trial studies on how the PEOX-based polymer encapsulated paclitaxel FID-007 (FID-007) affects the immune cells around the tumor patients with head and neck squamous cell carcinoma. The active drug in FID-007 is paclitaxel, an established chemotherapy drug that has be…
Phase 1 • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:26 UTC
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Could your Diet's antioxidants protect your metabolism? study digs into national data
Knowledge-focused CancelledThis cross-sectional study draws on data from the National Health and Nutrition Examination Survey (NHANES) database. The primary objective is to investigate the associations between the Composite Dietary Antioxidant Index (CDAI) and overweight/obesity, as well as the related met…
Sponsor: University-Town Hospital of Chongqing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Fat emulsion could be new weapon against pesticide poisoning
Disease control CancelledAim of the study: To assess the role of intralipid emulsion in the acute man-agement of organophosphorus toxicity and its benefits in de-creasing mortality rates among victims.
Phase 2/3 • Sponsor: Amani Hassan Abdel-Wahab • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Electric rowing machine study for paralysis pulled before it began
Symptom relief CancelledThe main objective of this project is to measure the increase in aerobic physical and metabolic capacities with a 6-month training on a rower assisted by electrostimulation of lower limbs in a population of adults with traumatic paraplegia.
Sponsor: UGECAM Rhône-Alpes • Aim: Symptom relief
Last updated Jun 26, 2026 19:11 UTC
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Night shift survival: coaching may keep ER doctors awake and alert
Knowledge-focused CancelledThe purpose of this study is to determine whether personalized lifestyle coaching minimizes the negative impact of circadian disruption on performance and recovery in emergency medicine physician trainees during night shifts.
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New drug lebrikizumab put to the test in healthy chinese participants
Knowledge-focused CompletedThe main purpose of this study is to determine the tolerability and side effects related to lebrikizumab comparing with placebo given as a single dose administered under the skin to healthy Chinese participants. The study will also assess how fast lebrikizumab gets into the blood…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:52 UTC
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3D-Printed gadget aims to simplify inhaler use for lung patients
Knowledge-focused CancelledThe purpose of this study is to investigate the auxiliary benefits of three-dimensional printed activating assistive devices for soft-mist inhaler on patients' utilization habit.
Sponsor: Fu Jen Catholic University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Bone marrow collection methods put to the test in small hip study
Knowledge-focused Recruiting nowSix patients with diagnosed bone loss of the hip who have consented to minimally invasive repair will be approached to participate in the study. Participants will have the liquid portion of bone marrow collected using the Zimmer Biomet Biocue system, which is the standard system …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Healthy volunteers test new rilzabrutinib tablet formulation
Knowledge-focused CompletedThis is a cross-over, Phase 1, 4-arm study. The purpose of this study is to measure the relative bioavailability and food effect of crystalline formulation rilzabrutinib and amorphous formulation rilzabrutinib in healthy male and female participants aged 18 to 55 years of age. T…
Phase 1 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:44 UTC
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Which colonoscopy prep is best? taiwan study pits two cleaners Head-to-Head
Knowledge-focused CompletedThis study aims to compare the intestinal cleansing efficacy, safety, tolerability, and acceptability of sodium picosulfate/magnesium citrate and polyethylene glycol in Taiwan.
Sponsor: Fu Jen Catholic University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New drug flonoltinib maleate tested for safety in healthy people
Knowledge-focused CompletedEvaluate the safety , tolerability and pharmacokinetics of Flonoltinib Maleate tablets in a single increasing dose oral administered to healthy adult Chinese subjects.Subjects will divide into experimental group and placebo group, conduct single oral administration safety and tol…
Phase 1 • Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Spine device study pulled before it began
Knowledge-focused CancelledThe purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.
Sponsor: Aesculap AG • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:03 UTC