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127005 trials found · Page 6201 of 6351
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Does breakfast change how this pain drug works? new study investigates
Knowledge-focused CompletedThe primary purpose of this study is to evaluate the effect of a high-fat, high-calorie meal on the relative bioavailability of NAL ER following single oral doses.
Phase 1 • Sponsor: Trevi Therapeutics • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Drug combo safety check in healthy volunteers
Knowledge-focused CompletedThis is a Phase 1 study to investigate safety and pharmacokinetics of ABBV-722 and Upadacitinib following multiple oral doses in healthy adult participants.
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Tooth wear mystery: gum shape and brushing habits under the microscope
Knowledge-focused CompletedThis observational study aims to investigate the relationship between periodontal morphology, oral hygiene habits, and non-carious cervical lesions (NCCLs) in adults aged 18-65 years. The main questions it aims to answer are: Is there an association between periodontal soft tiss…
Sponsor: Bilecik Seyh Edebali Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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New drug ORX489 put to the test in healthy adults
Knowledge-focused Recruiting nowCharacterize the safety, tolerability and pharmacokinetics of ORX489 following single and multiple doses.
Phase 1 • Sponsor: Centessa Pharmaceuticals (UK) Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New drug ENX-104 put to the test in healthy people
Knowledge-focused CompletedThe study is designed to evaluate the relative bioavailability, safety, and tolerability of a single dose of ENX-104 administered orally as a solution fasted, a tablet fasted, or a tablet with a high fat meal in healthy participants
Phase 1 • Sponsor: Engrail Therapeutics INC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Healthy men needed to test new Injection's safety
Knowledge-focused Recruiting nowEvaluate the safety, tolerability, PK/PD and immunogenicity characteristics of a single subcutaneous HEC-151 Injection solution in healthy participants
Phase 1 • Sponsor: Sunshine Lake Pharma Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Gut check: can oil change your microbiome?
Knowledge-focused Recruiting nowThis is a single-center, single-arm study, aiming at enrolling 25 healthy adult participants to evaluate chronic effects of oil. Specifically, we aim to assess the impact on gut microbiome after a one-month intervention with oil.
Sponsor: Société des Produits Nestlé (SPN) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Brain and hand: study links thinking to injury recovery in seniors
Knowledge-focused Not yet recruitingConsidering the complex structure of hand-forearm injuries and the long rehabilitation process, it is important to investigate factors associated with recovery in geriatric individuals. Therefore, this study aimed to examine the relationship between cognitive status and functiona…
Sponsor: Pamukkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New prostate drug enters early safety testing
Knowledge-focused CompletedA Clinical trial to compare and evaluate evaluate the pharmacokinetics and safety of CKD-846
Phase 1 • Sponsor: Chong Kun Dang Pharmaceutical • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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New drug KT-579 enters first human tests – no disease, just safety check
Knowledge-focused Recruiting nowThis is a first-in-human study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of single and multiple dose levels of KT-579 in healthy male and female adult participants.
Phase 1 • Sponsor: Kymera Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Thirsty for answers: new study pits electrolyte drinks against plain water
Knowledge-focused CompletedIn this study, the impact of two electrolyte hydration stick products (Hydramin containing an electrolyte/amino acid formulation and an identical electrolyte product with the amino-acids replaced with carbohydrate, dextrose) dissolved in 1 liter of water will be assessed and comp…
Sponsor: University of Memphis • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Do future dentists discriminate against HIV patients? new survey aims to find out
Knowledge-focused Not yet recruitingThe purpose of this multicentric study was to assess the attitude of Italian dental students towards HIV-infected patients. In particular, the level of discomfort perceived during the treatment, any discriminatory attitude on their part, their level of knowledge of the disease an…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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AI heart helper: will doctors use it?
Knowledge-focused Not yet recruitingThe goal of this observational study is to learn if an ai-assistive algorithm would be useful in patients who are under suspicion of coronary disease. The main question it aims to answer: What proportion of patients would clinicians see fit to order an ai-assistive algorithm if …
Sponsor: Heart Input Output Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Bigger leg muscles, better performance? new study investigates
Knowledge-focused Recruiting nowThe aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults. In addition, these physical performance measures will be compared between male and female participant…
Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Can a friendlier message get more patients into research?
Knowledge-focused Recruiting nowThis platform trial aims to evaluate the effectiveness of different messaging strategies within a MyChart messaging program for research recruitment. MyChart is a patient portal system within the Electronic Medical Record (EMR), and messages can be sent directly to patients about…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Can a quick online quiz reliably track your Well-Being?
Knowledge-focused Recruiting nowThis study aims to establish the test-retest reliability of the WB6Dim digital self-assessment tool across its eight well-being dimensions, using a 3-day interval protocol designed to minimize the probability of genuine well-being changes between assessments. Participants comple…
Sponsor: Clover Link • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Healthy men help test new Drug's safety
Knowledge-focused CompletedA randomized, double-blind, placebo-controlled, study to assess the safety, tolerability, and PK of MTX-463 when administered via SC injection in healthy adult males.
Phase 1 • Sponsor: Mediar Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New dental liner aims to ease Post-Filling tooth pain
Symptom relief Stopped earlyThis is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a procedure called direct pulp capping (DPC) if there…
Sponsor: Solventum US LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New drug LAD106 enters first human safety tests
Knowledge-focused Recruiting nowThe main aim of this study is to assess the safety, tolerability, pharmacokinetics (PK), immunogenicity and pharmacodynamics (PD) of single ascending doses of LAD106 (Part A) and multiple ascending doses of LAD106 (Part B) in human healthy participants.
Phase 1 • Sponsor: Almirall, S.A. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can a playlist get kids moving more? new study tests Music's power in PE
Knowledge-focused CompletedThe goal of this clinical trial is to investigate whether asynchronous music can improve outcomes of an 8-week long sport based youth development program. The main questions it aims to answer are: * Does music increase step count during each lesson? * Does music create a larger …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC