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127005 trials found · Page 6121 of 6351
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Herbal medicine safety under the microscope in korean hospitals
Knowledge-focused Stopped earlyProspective observations on safety of the herbal medicines regarding liver and kidney injuries at inpatient setting of four sites in South Korea which are located at each quadrant of the country. In a previous study (PMID 28634823), six women presented liver injuries by herbs and…
Sponsor: Korea Institute of Oriental Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:21 UTC
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Large study checks cancer risk in arthritis drug abatacept
Knowledge-focused CompletedThe purpose of this study is to collect real-world data in order to estimate the frequency of overall malignancies, melanoma, basal cell carcinoma, and squamous cell carcinoma in participants with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) enrolled in the SRQ Register…
Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Grape-Soy combo may reshape your gut bugs
Knowledge-focused CompletedThe overall purpose of this study is to evaluate the effect of nutritional supplementation with a well-characterized preparation of Concord grape polyphenol-soy protein isolate (GP-SPI) on the composition of the gut microbiota.
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive global heart study launches to see what really works
Knowledge-focused By invitation onlyISACS ARCHIVES network is part of ISACS TC (NCT01218776) health care program. It is a collaborative network of research centers that support the rapid development of new scientific information and analytic tools. The ISACS ARCHIVES network assists health care providers, scientist…
Sponsor: University of Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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What’s it like to live with bvFTD? researchers ask patients directly
Knowledge-focused CompletedThe VOICE Of bvFTD study is a telephone interview research study about life with or at risk for behavioral variant frontotemporal dementia (bvFTD). The study aims to understand how bvFTD impacts individuals' day to day lives, how people think about themselves, and what challenges…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New jaw fixation device tracked in global registry
Knowledge-focused CompletedThe goal of this registry is to evaluate the performance of the MatrixWAVE(TM) MMF system in patients suffering from non-condylar and/or condylar fractures. The evaluation will focus on the clinical performance in terms of : * surgical technique * application time * intra- and p…
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:24 UTC
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Lung cancer and sleepless nights: new study investigates
Knowledge-focused Recruiting nowThis study evaluates how common insomnia (difficulties with sleep) is in patients with lung cancer that has spread from where it first started (primary site) to other places in the body.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Drunk patients can't guess their BAC — study aims to use the gap to spark change
Knowledge-focused CompletedMany patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC). The hypothesis of the study is that self-estimation of BAC …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Bloating relief? tiny trial tests antibiotic for stomach paralysis
Symptom relief Stopped earlyResearchers are trying to determine if subjects with diabetic gastroparesis and symptoms of bloating will have a greater improvement in bloating symptoms when treated with rifaximin.
Phase 2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New dental implant study tests which surface helps teeth stay put
Disease control CompletedThe observed medical device in this study were SGS P7D Dental implant. The device replaces the lost tooth root, and provides support for the dental bridges and crowns, or overdenture replacements. This medical device provides the opportunity to to replace partial or complete miss…
Sponsor: SmileDent Kft. • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can friendly gut bacteria beat superbugs? new study explores natural decolonization
Knowledge-focused CompletedThis study is to identify and isolate well-defined microbials (non-ESBL E. coli) in an observational setting exploring natural gastrointestinal decolonization of humans colonized with ESBL E. coli.
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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First human tests begin for new oral drug LY3502970
Knowledge-focused CompletedThe main purposes of this study are to determine: * The safety of LY3502970 and any side effects that might be associated with it. * How much LY3502970 gets into the bloodstream and how long it takes the body to get rid of it. This study has 5 parts (A, B, C, D, and E). Parts A…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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New sensor could make blood gas monitoring easier
Diagnosis CompletedThis study aims at validating new optical transcutaneous sensors to evaluate tissue capnia (CO2 partial pressure) and oxygenation (blood oxygen saturation) by comparing them to standard laboratory measurements (end tidal CO2 measurements and oxygen saturation by near-infrared spe…
Sponsor: University Hospital, Grenoble • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Tiny study probes why shoulder stiffness returns after birth nerve injury surgery
Knowledge-focused Stopped earlyPOPB is a consequence of the stretching of the nerve roots (C5, C6 + / C7, C8 or T1) of the brachial plexus at birth. One third of patients will have sequelae. The most common is the appearance of a deficit of passive and active mobilities in the movements in external rotation of…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Feeding through a tube vs. vein: which heals gut leaks faster?
Disease control Stopped earlyThe incidence of clinically significant anastomotic leaks (AL) after upper gastrointestinal (GI) surgery is approximately 4 % - 20 %, and the associated mortality can be as high as 80 % . Nutritional support is a key component of therapy in such cases, related to high prevalence …
Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Brain training task may reveal why opioid addiction is so hard to beat
Knowledge-focused Recruiting nowBackground: People with addictions often find it hard to choose the long-term benefits of abstinence over the short-term effects of using drugs. Researchers think this is partly due to parts of the brain involved in certain types of learning and decision-making. Researchers want…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Sep 09, 2026 17:00 UTC
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Virtual shopping game tested to boost Seniors' brain power
Knowledge-focused Stopped earlyOlder adults could benefit from computer serious games as a strategy for improving not only their cognitive functions but also their functioning and performance in daily activities, which are often compromised with age. A computer serious game is one designed for a primary purpos…
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New blood pressure test could help kidney patients
Knowledge-focused CompletedThe investigators hypothesize that the Systolic Foot-to-Apex Time Interval (SFATI) method will be accurate for measurement of systolic blood pressure with marked arterial stiffness as seen in patients with severe renal impairment. Also that the presence of arterial calcifications…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Kidney cancer drug study halted after just 6 patients
Knowledge-focused Stopped earlyPatients treated on the first line of Sunitinib-targeted therapy for metastatic kidney cancer. Collection of additional blood tubes during routine blood tests for patient follow-up, to evaluate the plasma concentration of Sunitinib and its active metabolite desethyl-Sunitinib (D…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Heart procedure registry aims to improve care
Knowledge-focused Recruiting nowThis registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion. The primary goal is to evaluate safety, efficacy, and clinica…
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC