Can friendly gut bacteria beat superbugs? new study explores natural decolonization
NCT ID NCT04764500
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study followed 39 travelers to Southeast Asia to see if their guts naturally clear a type of antibiotic-resistant E. coli (ESBL E. coli) over time. Participants provided stool samples before and after travel and up to a year later. The goal was to understand how the body's own microbes might help push out resistant bacteria.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could point toward using harmless E. coli to help clear resistant bacteria from the gut naturally.
- What could go wrong
- This is a small observational study, not a treatment trial. It only looks at natural decolonization, so it may not lead to a therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Basel, Division of Clinical Microbiology
Basel, 4031, Switzerland