Can friendly gut bacteria beat superbugs? new study explores natural decolonization

NCT ID NCT04764500

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 39 travelers to Southeast Asia to see if their guts naturally clear a type of antibiotic-resistant E. coli (ESBL E. coli) over time. Participants provided stool samples before and after travel and up to a year later. The goal was to understand how the body's own microbes might help push out resistant bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could point toward using harmless E. coli to help clear resistant bacteria from the gut naturally.

What could go wrong

This is a small observational study, not a treatment trial. It only looks at natural decolonization, so it may not lead to a therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

escherichia coli infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Basel, Division of Clinical Microbiology

    Basel, 4031, Switzerland