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127005 trials found · Page 6104 of 6351
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Blood samples shed light on mysterious muscle disease
Knowledge-focused CompletedThe goal of this prospective observational study is to create a network repository of clinical data and biological samples to help researchers learn more about myasthenia gravis.
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedMedical functional imagery seems to demonstrate that patients suffering from complex regional pain syndrome (CRPS) have cortical modifications that alter their motor (or mental) imagery capacities. Nowadays, the use of motor imagery exercises are used in conventional rehabilitati…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Experimental lung inflammation treatment trial shuts down after just one patient
Disease control Stopped earlyThis phase II trial studies how well infliximab and intravenous immunoglobulin therapy work in treating patients with pneumonitis that does not respond to steroid treatment. Immunotherapy with monoclonal antibodies such as, infliximab, may induce changes in body's immune system a…
Phase 2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Tooth infection study reveals key inflammation clues
Knowledge-focused CompletedA total of 185 subjects were divided into three categories: AP group (n=85), CP group (n=50) and healthy control group (n=50). The AP group was divided into 3 subgroups according to abscess scoring (AS-PAI) based on the periapical index. The CP group was divided into 4 subgroups …
Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Massive data dive aims to improve GI care
Knowledge-focused By invitation onlyThis study will be a retrospective, registry study collecting data of patients who were diagnosed with benign or malignant gastrointestinal diseases. Data will be collected from patient's chart retrospectively once the patients have completed proper treatment follow up with physi…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New EyeCheck device put to the test for glaucoma monitoring
Knowledge-focused Stopped earlyTo investigate whether the new applanation tonometer (EyeCheck monitor) can provide intraocular pressure (IOP) measurements comparable to those of traditional tonometers such as the Goldmann applanation tonometer and the Tonopen.
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Cast duration may boost skin graft success
Knowledge-focused CompletedFibula free flaps (FFF) and radial forearm free flaps (RFFF) are necessary to reconstruct parts of the face after cancer surgery, traumas, or debilitating infections. Oftentimes, after we take the flap from the arm or leg, there is a large skin defect that must be filled. A split…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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E-Cig study reveals nicotine delivery differences
Knowledge-focused CompletedThe purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant device settings and different e-liquid concentration…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Are Moms-to-Be with diabetes missing key nutrient?
Knowledge-focused CompletedIodine supplementation during pregnancy is recommended by the high health authority and by the World Health Organization during pregnancy. We would like to know if this supplementation is prescribed in a manner consistent with the recommendations in women diagnosed with gestation…
Sponsor: Centre Hospitalier Sud Francilien • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Leftover surgery tissue could unlock secrets of hardening arteries and bones
Knowledge-focused Recruiting nowAlthough it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to c…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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CBD cream or oil: does it reach your bloodstream?
Knowledge-focused CompletedThe present cross-over study investigated whether cannabidiol (CBD) or its metabolites and delta-9-tetrahydrocannabinol (THC) can be detected in the systemic circulation following a single topical application of a natural hemp extract-based cosmetic (NHEC) consisting of CBD and m…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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AI scans could help surgeons avoid overdosing muscle relaxants
Knowledge-focused CompletedDeep neuromuscular blockade has benefits in various surgical procedures and reduces postoperative pain. While neuromuscular blockade dosages are often based on the patient's actual body weight, body composition can vary significantly depending on age, gender, and individual exerc…
Sponsor: Seoul National University Bundang Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Heart failure drug use tracked in 13,660 remote monitoring patients
Knowledge-focused CompletedThis observational cohort study evaluates temporal trends and determinants of sodium-glucose cotransporter 2 inhibitor (SGLT2i) prescriptions among adults with chronic heart failure enrolled in a nationwide remote monitoring program in France between 2021 and 2024. The analysis e…
Sponsor: Satelia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Year-Long training vs One-Day course: which better prepares nurses for newborn emergencies?
Knowledge-focused Stopped earlyThe Neonatal Resuscitation Program (NRP) recommends providers renew their certification every 2 years. However, many Neonatal Intensive Care Units (NICUs) in Canada face challenges of significant budget cuts in training and a large number of caregivers to train with a high turnov…
Sponsor: Ahmed Moussa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Healthy volunteers to receive ketamine in brain study
Knowledge-focused Ongoing50 healthy volunteers (HV) will participate in 2 identical ketamine-induced pharmacoBOLD (phBOLD) sessions at least 7 days apart. On both days, clinical assessments will be performed following removal of the subject from the scanner. HV will be discharged home after clearance by…
Phase 1/2 • Sponsor: New York State Psychiatric Institute • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Brain surgery breathing trick safe for kids, study finds
Knowledge-focused CompletedThis study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position. The findings indicated that the application of PEEP did not…
Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Ultrasound angle may predict IUD displacement risk
Knowledge-focused CompletedThe investigators conducted a case-control study between December 2020-June 2021 at Istanbul Health Sciences University Kanuni Sultan Suleyman Training and Research Hospital family planning outpatient clinics. One hundred and forty-three patients who had copper intrauterine devic…
Sponsor: Kanuni Sultan Suleyman Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:28 UTC
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21,000 patients enrolled in hospital registry to uncover Long-Term health trends
Knowledge-focused OngoingThis study is a prospective medical registry (the SOFIT Registry) that enrolls all patients hospitalized in various departments of the Tula Regional Clinical Hospital in 2021. The primary objective of the study is to analyze demographic, clinical and anamnestic characteristics o…
Sponsor: National Medical Research Center for Therapy and Preventive Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Study reveals hidden differences in Kids' lung diseases during exercise
Knowledge-focused CompletedCystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are genetic diseases characterized by chronic respiratory tract infections. In both diseases, impaired mucociliary clearance, recurrent respiratory infections, and persistent inflammation lead to progressive deterioration …
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Study reveals key clues to survival after severe injury
Knowledge-focused CompletedTrauma is a public health concern that causes serious financial and medical burdens worldwide. According to the World Health Organization, 4.4 million people die from traumatic injuries each year which account for about 8% of global deaths. Traumatic injuries are among the most c…
Sponsor: Melike Cengiz • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC