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127005 trials found · Page 6086 of 6351
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Tiny teeth bumps keep popping off? scientists investigate
Knowledge-focused CompletedThis prospective clinical study evaluated the incidence of composite attachment loss in patients undergoing clear aligner treatment and identified patient-, tooth-, and treatment-related factors associated with attachment debonding. Twenty-one patients were followed for six month…
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Mouth score may predict gallbladder surgery outcomes
Knowledge-focused CompletedTo predict the majority of Mallampati score for the patients in Qassim region who undergoing Laparoscopic Cholecystectomy Surgery.
Sponsor: Qassim University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Can a morals class make better nurses? new study says maybe.
Knowledge-focused CompletedThe objective of this historical control trial is to evaluate the effectiveness of an Ethics and Moral Course, based on the Ashridge training model, in newly graduated nurses. The primary questions it aims to address are: (1) What is the impact of integrating moral education into…
Sponsor: Eye & ENT Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Digital face scans could speed up dental crown fittings
Knowledge-focused CompletedRegardless of the fabrication workflow occlusal adjustments seem to be inevitable during delivery of indirect fabrication of the restoration. This has been attributed to snowballing of discrepancies due to multiple procedures for information transfer between the clinician and the…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Heartburn and arthritis drugs tested against COVID-19
Disease control CompletedThis master protocol serves as a common reference for the inpatient and outpatient clinical studies that share common elements.
Phase 2 • Sponsor: Leidos Life Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Scleroderma hand study reveals key differences in disability
Knowledge-focused CompletedSystemic sclerosis is an autoimmune disease in which the hand is responsible for 75% of the overall disability. Management is based on systemic treatments combined with kinesitherapy aimed at maintaining joint amplitudes, improving muscle strength and preventing stiffness. The ai…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Practice makes perfect: simulation training boosts new Surgeons' skills
Knowledge-focused CompletedSimulation training with the Miya Model will improve Operating Room performance of Vaginal Hysterectomy (VH) in novice surgeons and this phase of the study is designed to test that.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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20,000 people surveyed to speed up mental health research
Knowledge-focused Recruiting nowTRIAGE-Psych is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored psychiatry clinical trials.
Sponsor: Adams Clinical • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Radioactive treatment for bone pain in advanced prostate cancer tested, but study stopped early
Symptom relief Stopped earlyThis phase II trial studies the effect of Sn-117m-DTPA on bone pain in patients with prostate cancer that has spread to the bones. Sn-117m-DTPA is a radioactive therapeutic agent that localizes to bones when given to patients. Sn-117m-DTPA may help reduce bone pain in patients wi…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Tiny study checks blood pressure drug in kids
Disease control CompletedThe main aim of this study is to check for side effects from treatment with azilsartan and how well azilsartan controls blood pressure in children from 6 to less than 16 years old with high blood pressure. The study sponsor will not be involved in how the participants are treate…
Sponsor: Takeda • Aim: Disease control
Last updated Jun 26, 2026 15:51 UTC
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Knee surgery may change ankle pain – small study investigates
Knowledge-focused CompletedChanges in demographics and physical activities of the young population have increased the number of patients with medial unicompartmental knee osteoarthritis (OA) requiring surgical intervention. High tibial osteotomy (HTO) have shown good clinical results in restoring lower ex…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Migraine drug rimegepant's pregnancy safety under review
Knowledge-focused OngoingThe purpose of the study is to evaluate the risk of pregnancy and infant outcomes among women with migraine exposed to rimegepant during pregnancy and in two rimegepant unexposed comparator groups.
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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New dutch survey aims to better measure chest deformity impact
Knowledge-focused Recruiting nowA questionnaire that can measure disease severity from the patients perspective in patients with pectus excavatum already exists in English (Pectus Excavatum Evaluation Questionnaire; PEEQ). This questionnaire was recently translated into Dutch. Before this Dutch version can be u…
Sponsor: Erik de Loos • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Social exclusion may mess with memory in ADHD kids
Knowledge-focused CompletedAssess the effect of exposure to a situation of social exclusion or ostracism on the prospective memory of children with ADHD
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can a new MRI shortcut cut scan time without sacrificing quality?
Knowledge-focused CompletedPatients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added. MRI of routine care includes at least the following sequences: * 3D T1 TFE (2 minutes) * T2 TSE …
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Scientists map where metallic taste hits the tongue
Knowledge-focused CompletedThis is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better u…
Sponsor: Centre Hospitalier de Valence • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:22 UTC
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Large ICU study sheds light on common breathing problem
Knowledge-focused CompletedHypercapnia is a frequent clinical situation defined as an elevation of the partial pressure of carbon dioxide (PaCO2) above 45 mmHg. Several physiopathological parameters such as respiratory minute volume, dead space volume or CO2 production influence the PaCO2. Therefore, hyper…
Sponsor: French Society for Intensive Care • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:02 UTC
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Robot-Assisted spine surgery in kids: a safety check
Knowledge-focused Recruiting nowCreation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across participating study institutions. Eventually, an educatio…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Kidney function may reveal hidden clues about high blood pressure
Knowledge-focused CompletedHypertension is a public health concern and affects nearly a third of the French population. It can be complicated by visceral impact (including brain, heart and kidney complications) as well as on vessels especially large arteries, responsible for arterial stiffening. There are …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:58 UTC
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New asthma shot depemokimab tested in chinese volunteers
Disease control CompletedThis single dose pharmacokinetic (PK) study aims to investigate the PK, safety, tolerability and immunogenicity of two dose levels of GSK3511294 administered subcutaneously in Chinese healthy participants
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC