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127005 trials found · Page 5991 of 6351
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Tiny tooth ridges may change how we see a smile
Knowledge-focused CompletedThis study aimed to evaluate the role of the mamelon effect on the perception of smile esthetics. A single portrait image was digitally modified by using the Photoshop CC (Adobe, USA) software program to create the mamelon effects at the incisal edge of maxillary incisors. Length…
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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3D-Printed tooth restorations face off against milled ones in new trial
Disease control By invitation onlyAim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation following the FDI criteria and three-dimensional digit…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Will tylenol fool your glucose monitor? new study investigates
Knowledge-focused CompletedThe primary objective of the study is to evaluate the interference effect of acetaminophen (APAP) on the Biolinq MicroArray Intradermal Continuous Glucose Biowearable System during a single in-clinic day on Day 3 of the sensor wear period. All participants will be asked to wear …
Sponsor: Biolinq Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Doctors' views on hidden inflammation in heart and kidney patients surveyed
Knowledge-focused CompletedThis is a survey-based study with the objective to understand the awareness, perceptions and potential clinical management patterns among Chinese cardiologists and nephrologists towards the role of systemic inflammation in patients with ASCVD and CKD in real-world clinical settin…
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Titanium dentures tested for speech clarity in small trial
Knowledge-focused Recruiting nowPartial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys. However, advancements in digital dentistry have in…
Sponsor: Badr University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:44 UTC
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Do kids with hearing loss know why? new study investigates
Knowledge-focused CompletedThis is a qualitative study to investigate children and their care-givers knowledge about the underlying aetiology of the childrens hearing loss. Both children and care-givers are given forms with questions about the type and level of hearing loss, if they know the cause and if i…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Drill boosts paramedic confidence in emergency airway skills
Knowledge-focused CompletedThe goal of this observational study is to learn about the effects of training an Emergency Reflex Action Drill (ERAD) for Emergency Surgical Airway (ESA) in Dutch paramedics. The main question it aims to answer is: \- Does training an ERAD improves self-confidence in performing…
Sponsor: Erasmus Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Hair follicle cream may cut redness after facelifts and lasers
Knowledge-focused Recruiting nowNon-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Sponsor: Acorn Biolabs Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Finger sensor vs. arm cuff: which matches the gold standard best?
Knowledge-focused CompletedThis is an observational study simultaneously comparing finger-sensor and oscillometric with intra-arterial blood pressure measurements in patients having low- to moderate-risk non-cardiac surgery.
Sponsor: University of Hamburg-Eppendorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Experimental donor CAR-T therapy tested in lymphoma – trial halted early
Disease control Stopped earlyThe purpose of this study is to evaluate the safety and preliminary efficacy of ATA3219 in participants with relapsed/refractory (R/R) B-cell non-Hodgkin Lymphoma (NHL).
Phase 1 • Sponsor: Atara Biotherapeutics • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Scar treatment TRTP-101 tracked for Long-Term safety
Symptom relief OngoingCIC101-01-LT is a long-term follow-up study of subjects treated with TRTP-101 and will evaluate the long-term safety and efficacy of TRTP-101.
Sponsor: CellinCells • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Newborn tumor study: can prenatal scans get the diagnosis right?
Knowledge-focused CompletedCongenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor. Indeed, some histologically benign tumors may have lethal potential in utero (e.g. sacrococcygeal teratomas…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:56 UTC
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Oxygen sensors could soon track your breathing too
Knowledge-focused CompletedThe study will be conducted in hospitalised patients who undergo spot-check monitoring of vital signs as part of their routine care.
Sponsor: Philips Clinical & Medical Affairs Global • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:33 UTC
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New lens shows promise for clearer vision after cataracts
Knowledge-focused CompletedThis study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit. Clinical evaluations will include administration of the AIOLIS and OSDI questionnaires,…
Sponsor: Mann Eye Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Healthy volunteers test new injection method for Infection-Fighting drug
Knowledge-focused CompletedThe Goal of these study is to evaluate and To compare the pharmacokinetics (PK) of the Test product (T) getting administered through prefilled syringe with on-body injector with Reference product as prefilled syringe following a single 6 mg dose administered through subcutaneous …
Phase 1 • Sponsor: Kashiv BioSciences, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Can MRS spot spinal cord problems? small study aims to find out
Knowledge-focused CompletedTo learn if MRS can effectively assess spinal cord lesions.
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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New antibiotic cocktail tested for safety in 60 volunteers
Knowledge-focused CompletedA phase 1, randomized, double blind, placebo controlled drug-drug interaction, pharmacokinetics and safety study of cefiderocol in combination with xeruborbactam in healthy adult participants
Phase 1 • Sponsor: Qpex Biopharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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10,000 volunteers needed to help scientists understand addiction
Knowledge-focused Recruiting nowBackground: People who will participate in research studies need to undergo proper screening, evaluation, and assessment (SEA). SEA helps keep those who participate in studies safe. It also helps ensure accurate study results. The National Institute on Drug Abuse (NIDA) Intramur…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Necklace camera watches what you eat, no audio needed
Knowledge-focused Recruiting nowThis study utilizes a small, privacy-conscious wearable device intended to monitor human behaviors. The device is worn around the neck, capturing the wearer's head and upper torso within its field of view, and records color images without audio. Participants visit the lab for con…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New cancer Drug's interaction with common meds under microscope
Knowledge-focused CompletedThe goal of the study is to see what happens to levels of midazolam and digoxin in a person's body over time (a pharmacokinetic or PK study). Researchers will compare what happens to midazolam and digoxin in the body when it is given with and without another medicine called calde…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC