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127005 trials found · Page 5776 of 6351
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HIV drugs may weaken bones: new study investigates
Knowledge-focused Stopped earlyOsteopenia and osteoporosis are increasingly reported in HIV-infected patients, and appear to be more frequent than in general population. However, pathogenesis remains unclear, and published studies still give non concordant results. We therefore started a prospective study, to…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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1,598 RA patients enrolled in quest to personalize treatment
Knowledge-focused OngoingThe goal of the present study is to establish a prospective observational cohort of Rheumatoid Arthritis patients in order to 1. Determine and validate biomarkers that predict drug response and toxicity in RA. 2. Determine and validate biomarkers that predict disease activity an…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can juice plus+ help ovarian cancer survivors?
Disease control OngoingThe goal of this clinical research study is to see if ovarian cancer patients who add Juice PLus+ and Juice Plus+ Complete to their diets have better outcomes when compared to ovarian cancer patients who receive only dietary counseling alone.
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can a better scan spot hidden prostate cancer?
Knowledge-focused Recruiting nowThis study will use PET scans, which is a type of x-ray test that uses a radiotracer, to see whether these scans may be better able to find places in the body where your prostate cancer may have spread.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Long-Term study sheds light on rare bone and hormone disorder
Knowledge-focused OngoingWe, the researchers, are following the natural history of Albright hereditary osteodystrophy. We have found that growth hormone deficiency is very common in patients with pseudohypoparathyroidism type 1A, which falls under the broader condition termed Albright hereditary osteodys…
Sponsor: Connecticut Children's Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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AI analyzes 700 sarcoma cases to unlock survival secrets
Knowledge-focused CompletedApplication of computational statistics and machine learning methods to data derived from electronic health records of patients diagnosed with sarcoma.
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Gene hunt for lung scarring disease opens to 2,000 volunteers
Knowledge-focused Recruiting nowThe purposes of this study are: * to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis; * to determine if specific genetic traits account for differing patterns of inflammation and scar tissue that has formed in the …
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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3000 bipolar patients join landmark norwegian study
Knowledge-focused Recruiting nowTo describe the broad spectrum of Bipolar Disorder patients admitted to out-patient and in-patient psychiatric departments in Norway. Include all admitted Bipolar patients both with and without co-morbid disorders.
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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8,000 volunteers help uncover colon polyp risks
Knowledge-focused CompletedRATIONALE: Collecting and storing samples of tissue, blood, and other body fluids to test in the laboratory and gathering information about health and lifestyle from participants may help doctors learn more about cancer risk factors. PURPOSE: This clinical trial is looking at bi…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New registry aims to unlock secrets of rare adrenal cancer
Knowledge-focused Recruiting nowBasic objective of the German Adrenocortical Carcinoma Registry is to improve the care of patients with adrenocortical cancer. The registration of as many patients as possible helps to collect data for the prognosis and prospects of success regarding different treatment plans. Th…
Sponsor: University of Wuerzburg • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Phone therapy shows promise for depression in ovarian cancer patients
Symptom relief OngoingThe goal of this behavioral research study is to find a quick and effective way to identify depression in patients with ovarian, peritoneal, or fallopian tube cancer. Another goal of this study is to compare an intervention program with "enhanced" standard care to see which may b…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Brain stimulation for Parkinson's linked to weight gain – study investigates why
Knowledge-focused CompletedThe aim of this trial is to verify that neurostimulated parkinsonian patients gain weight and to study its link with an energetic balance change.
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Blood samples sought to unlock secrets of sickle cell disease
Knowledge-focused By invitation onlyThe collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general condi…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Massive PKD data collection aims to unlock secrets of kidney disease
Knowledge-focused Recruiting nowAutosomal dominant polycystic kidney disease (PKD) is the most common inherited kidney disease, affecting more than 400,000 people in the U.S. and 5 million people worldwide. PKD is the 4th most common cause of kidney failure requiring dialysis and/or transplantation. Over half o…
Sponsor: The Rogosin Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Anthrax secrets revealed: new study tracks infection and vaccine response
Knowledge-focused CompletedThis study will examine pathophysiology and immune response of anthrax in infected or exposed individuals to learn more about the disease symptoms, prevention and response to treatment. In addition, it will evaluate immune response to the anthrax vaccine AVA (Anthrax Vaccine Adso…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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New study aims to predict organ rejection before it happens
Knowledge-focused CompletedThe purpose of this study is to see what a lab test will show and if there is a way to predict which patients will be more likely to have rejection after receiving a liver transplant.
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Ancient herb vs. modern vitamins: which boosts heart health?
Disease control CompletedThis was a randomized controlled trial aimed to evaluate the effects of an herbal Ayurvedic herbal supplement in comparison to a Vitamin C/E supplement and an inert placebo on heart health. There were three treatment groups: Maharishi Amrit Kalash (MAK), vitamin C+E and the place…
Sponsor: Maharishi International University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Scientists hunt for genetic clues in head and neck cancers
Knowledge-focused Recruiting nowThe purpose of this study is to study the genetic profile of head and neck tumors and their relationship to treatment response and outcome
Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Scientists hunt for the gene behind rare brain disorder
Knowledge-focused Recruiting nowBased on our current understanding of Aicardi syndrome, the condition is hypothesized to occur due to a genetic change on the X-chromosome. The research team is investigating Aicardi syndrome to identify the specific gene location associated with the disorder. The investigators a…
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Scientists study mast cells to unlock mastocytosis mysteries
Knowledge-focused Recruiting nowThis study will examine growth factors that promote and inhibit mast cell proliferation resulting in mastocytosis, a disease of excessive mast cells in the body. These cells can release chemicals that cause itching, blisters, flushing, bone pain and abdominal pain. Patients up t…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 09, 2026 21:00 UTC