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127005 trials found · Page 5698 of 6351
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Which epidural catheter works best for Post-Surgery pain?
Symptom relief CompletedThe investigators hypothesize that multi-port thoracic epidural catheters will provide superior pain relief when compared to uniport catheters for post-surgical patients.
Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Morphine gel may offer direct relief for chemo mouth sores
Symptom relief Stopped earlyChemotherapy kills tumor cells but can also damage healthy cells and cause significant digestive disorders such as ulcers of the mouth, called mucositis. Mucositis are transient but their intensity may require special measures. Mucositis are painful and morphine gel or intravenou…
Phase 3 • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Blood test may predict heart attack Patients' future risk
Knowledge-focused CompletedThis prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Baby formula upgrade: could lactoferrin close the gap with breast milk?
Knowledge-focused CompletedBreast milk is the gold standard of early infant nutrition and breastfed infants have advantages in several short and long term outcomes compared to those formula-fed. The first aim of this study is to evaluate the effect of adding bovine lactoferrin to infant formula. The gener…
Sponsor: Umeå University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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New artery surgery shows promise for leg pain
Disease control CompletedEndarteriectomy is considered as the first line treatment of femoral bifurcation atheromatous lesions. Eversion technique, similar to that used for carotid bifurcation, is safe and possible for the majority of the femoral tripod lesions. The major advantage of the eversion techni…
Sponsor: Hôpital NOVO • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New spinal fluid test may sharpen Alzheimer's diagnosis
Diagnosis CompletedThe combined measurement of Ab42 and tau protein (total and phosphorylated) in the spinal fluid has been shown to be promising in the diagnosis of Alzheimer's disease (AD), and has justified its inclusion new diagnostic criteria. However, it can sometimes yield discordant results…
Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Scientists probe HIV's secret hiding spots in uganda
Knowledge-focused Recruiting nowBackground: Human Immunodeficiency Virus (HIV) is the virus that causes AIDS. HIV can hide in the blood for many years, even in people who have their HIV infection under control. HIV that is hiding in the blood is called the "latent HIV reservoir." Researchers want to find out m…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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New registry aims to sharpen use of precision radiation for cancer
Knowledge-focused CompletedThis prospective protocol will enroll patients with pathologically confirmed solid malignancies who receive stereotactic body radiation therapy (SBRT) for oligometastases, for consolidation after systemic therapy, prior to systemic therapy for the purposes of debulking, or in the…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:50 UTC
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Scientists collect tissue to unlock lung cancer secrets
Knowledge-focused Recruiting nowBackground: \- Lung cancer is the leading cause of cancer-related death worldwide. It causes more than one million deaths every year. Researchers want to gather tissue samples from people with lung and thymic cancers to understand the disease better. This may lead to new ways to…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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New study aims to map brain behavior in alcohol addiction
Knowledge-focused Recruiting nowBackground: \- Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a person s behavior. They want to develop tasks that can be done inside a scanner that can help them better understand these eff…
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Brain scans reveal how autism affects attention to emotions and change
Knowledge-focused CompletedSeveral studies seem to indicate that emotional attention and change-related attention are impaired in ASD. The goal of this study is to identify the relationships between those two types of automatic attention in visual and auditory modalities in subjects with ASD compared to he…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Eye test could reveal hidden blood vessel damage in heart and kidney patients
Knowledge-focused Recruiting nowPatients with high blood pressure (hypertension) and chronic kidney disease are at an increased risk of developing heart disease and strokes. Part of this risk is due to changes in the structure and function of the blood vessels throughout the body. It is thought that reducing hi…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Balloon treatment for clogged ear tubes shows promise in small study
Symptom relief CompletedThe study aim is to evaluate the tubal score on patients who suffer from obstructive dysfunction of eustachian tube before and after the eustachian tube dilatation.
Sponsor: University Hospital, Montpellier • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could tiny particles explain clot danger in kids with leukemia?
Knowledge-focused CompletedAcute lymphoblastic leukemia is the most common malignancy of the child. Current therapeutic strategies allow healing of over 80% of children. However these treatments are associated with toxicity, with a mortality of 1-2%. The most frequent complications, occuring during treatme…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Scientists probe lung microbiome to unlock COPD secrets
Knowledge-focused Recruiting nowThis is a cross sectional case controlled study to assess lung microbiome and inflammation in smokers with and without Chronic Obstructive Pulmonary Disease (COPD). Investigators will look at active bacterial metabolic pathways in the lower airways using metagenomic and metabolom…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Thousands tracked for decades to see how hip implants hold up
Knowledge-focused Recruiting nowThis long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
Sponsor: Corin • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can training reduce stigma in healthcare? new study tests Anti-Bias program
Knowledge-focused CompletedThis project is measuring the effectiveness of an anti-stigma intervention among primary care providers. Both staff and clients will be asked to complete survey data in order to measure the effectiveness. This is a randomized control trial in that three health centres will receiv…
Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Scientists hunt for hidden signs in blood cancers to personalize treatment
Knowledge-focused CompletedHEMATO-BIO-IPC-2013-015 is a monocenter prospective longitudinal study. Our aim is to define predictive clinical and biological factors in acute leukemia, myelodysplastic syndromes and myeloproliferative disorders by using genomics, genetics and epigenetics, in vitro and in vivo …
Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Study tracks walking decline in cerebral palsy as kids grow up
Knowledge-focused OngoingThe purpose of this study is to investigate longitudinally, the walking ability of individuals with cerebral palsy who are transitioning into adulthood and to cross-sectionally examine the health status of these individuals in the context of their walking ability. Young adults wh…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Dads included: new program aims to beat baby blues together
Knowledge-focused CompletedStudy hypothesis: Childbearing couples who receive the father inclusive psychoeducation program will have: (a) a lower level of depressive symptoms, (b) a higher level of marital relationship, and (c) a higher level of quality of life at 6 weeks, 6 months and one year postpartum …
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC